The subject of this case report, a 64-year-old white female, was treated for osteoporosis with oestrogens. She developed unequivocal systemic lupus erythematosus, from which she had suffered as a young woman and which had remitted with her menopause at 38. The close relationship of the relapses and remissions of her disease with her hormonal status underlines the importance of endocrine factors in the clinical expression of systemic lupus erythematosus.
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