The present study was undertaken to evaluate the ethanol extract of leaves of Bauhinia purpurea and unripe pods of Bauhinia purpurea for its protective effects on gentamicin-induced nephrotoxicity in rats. Nephrotoxicity was induced in Wistar rats by intraperitoneal administration of gentamicin 100 mg/kg/d for eight days. Effect of concurrent administration of ethanol extract of leaves of Bauhinia purpurea and unripe pods of Bauhinia purpurea at a dose of 300 mg/kg/d given by oral route was determined using serum creatinine, serum uric acid, blood urea nitrogen and serum urea as indicators of kidney damage. The study groups contained six rats in each group. It was observed that the ethanol extract of leaves of Bauhinia purpurea and unripe pods of Bauhinia purpurea significantly protect rat kidneys from gentamicin-induced histopathological changes. Gentamicin-induced glomerular congestion, blood vessel congestion, epithelial desquamation, accumulation of inflammatory cells and necrosis of the kidney cells were found to be reduced in the groups receiving the leaf and unripe pods extract of Bauhinia purpurea along with gentamicin. The extracts also normalized the gentamicin-induced increase in serum creatinine, serum uric acid and blood urea nitrogen levels. This is also evidenced by the histopathological studies.
Plant extracts have been used as a source of medicines for a wide variety of human ailments. the . Phytochemical analysis of flowers of ornamental plants of Chrysanthemum indicum L. and Calendula officinalis are very useful in identifyingnew sources of therapeutically important compounds like saponins, terpenoids, flavonoids and steroids are present in the flower extract of Chrysanthemum indicum L and carbohydrates, flavonoids, terpenoids are present in the flower extract of Calendula officinalis . Chrysanthemum indicum L :Hindi :Guldaudi, Sanskrit : Bahupatrika, Odiya: Shevathi Calendula officinalis: English : Marigold ,Hindi : Genda.
The objective of the current research work was to determine the anti inflammatory activity of Psidium guajava by the Human Red Blood Cell membranes stabilization method. The methanol and ethanol leaf extract of plant Psidium guajava were investigated for their invitro anti-inflammatory property by Human red blood cell membrane stabilization method. The prevention of hypotonocity induced HRBC membrane lysis was taken as a measure of a anti-inflammatory activity. The anti inflammatory activity of methanol and ethanol leaf extract of psidium guajava were compared to that of standard drug Diclofenac.Psidium guajava L. belongs to Myrtaceae.
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