An electrographic correlate of short-latent processes in the visual system corresponding to the ERG a-wave was detected in chronic experiments on awake rabbits. The formation of an early negative potential (ENP), small in amplitude, that precedes the positive component of the primary responses (PR) to light and is thus the earliest signal concerning the arrival of information from the retina was detected during a special recording regimen in the optic tract, superior colliculi, outer geniculate body, and visual cortex. The shift in the latent periods with respect to the onset of the development of the ERG a-wave comprised 2-3 msec in all the above structures. The suppression of all ERG components except the a-wave by glycine injected into the vitreous body was accompanied in all structures by the suppression of all PR components except the very initial ENR. Since the pre-excitatory inhibition of ganglionic elements corresponds to the ERG a-wave at the exit from the retina, the role of this inhibition in the transmission of information concerning the very first instant of the visual signal both to subcortical centers and the visual region of the cerebral cortex should be recognized.
The obtained data suggest that the process of ERG recovery involves compensatory mechanisms of the SO and SCH nuclei that enable partial recovery of the neurotransmitter activity of the retina.
Researching some aspects of functioning retina performance in conditions of pigmentary dystrophy (PD) will allow revealing a number of features regarding its existence and sequence of restoration both as respector and neural systems.Research objecture. To investigate dynamics of formation of electroretinogram (ERG) in conditions of retina PD. Materials and methods. Chronic experiments were conducted on awake rabbits for a month in the norm and condition of PD. Results. The received results testily that formation a – and b – ERG components in condition of PD was ambiguous. Amplitudes of a – waves higher (76,4%) than those of b – waves (44,4%). Conclusion. Partial recovery of ERG components is a result of the inclusion of retina backup mechanisms capable of withstanding pathological process and restoring vision.
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