Two adapti\•e al~:oritluns hased 011 exte11ded Kalman.filter.f'пr estimation oj'spec!fic growt/1 rate !J, collcentrations oj' Ьiomass Х and product Р j'or aerohic hatc/1 process o.f" ergocriptin Ьiosyntesis in dejiciency oj' 011-line iJ!f'пrmation j'пr state ~·ariables are syntlzesized. Тlze algorirlzms ejjiciency is pro\•ed hy simulatirm iJa•estigatirms 011 tl1e hasis oj'tl1e process model. Т11е esrimation accuracies oj' tl1e two algorirluns are comparell, tl1e estimates ohtainell hy one oj'tlze algorirlzms being compared wit/1 adapti~·e srare ohsen·er ones. Conc/usions about app/icahility oj' tlte prnposed a/goritlzms are made.
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