The displacement and stress fields caused by eigenstrains (thermal expansion, plastic strain, phase transformation, etc.) distributed uniformly inside a domain 8 of an infinitely extended anisotropic medium are expressed in a series form and also in an interesting integral form. These forms provide not only a method of stress analysis but also enable an investigation of Eshelby's proposition that the stress in an ellipsoidal domain is constant.The special case that SZ is a flat ellipse leads to an extremely simple result. Die Verschiebungs-und Spannungsfelder, die durch Eigendehnungen (thermische Ausdehnung, plastische Dehnung, Phasentransformation, etc.) verursacht werden, die gleichformig in einer Domane SZ in einem unendlich angedehntem Medium verteilt sind, werden in einer Reihenentwicklung und ebenfalls in einer interessanten Integralform ausgedruckt. Diese Formeln ergeben nicht nur eine Methode fur die Spannungsanalyse, sondern ermoglichen eine Untersuchung des Vorschlags von Eshelby, daB die Spannung in einer elliptischen Domane eine Konstante ist. Der Spexialfall, daB SZ eine flache Ellipse ist, fuhrt zu einem extrem einfachen Ergebnis. I) This research was supported by the Atomic Energy Commission through Northwestern 2, Leave of absence from Meiji University, Tokyo, Japan.University.

CIC-DUX4 and BCOR-CCNB3 fusion-gene-associated small round cell sarcomas account for a proportion of pediatric small round cell sarcomas, but their pathological features have not been sufficiently clarified. We reviewed a large number of soft tissue tumors registered at our institution, retrieved the cases of unclassified tumors with a small round cell component, and subjected them to histopathological, immunohistochemical, and gene profile analysis. We reviewed 164 cases of unclassified tumors with a small round cell component and analyzed them by RT-PCR and FISH. Tumors positive for a specific fusion-gene were also subjected to histopathological and immunohistochemical examinations. We identified 16 cases of BCOR-CCNB3/CIC-associated (CIC-DUX4 or CIC gene rearrangement-positive) sarcomas. These included seven BCOR-CCNB3 sarcomas and nine CIC-associated sarcomas. Heterogeneous elements included a myxoid spindle cell component in three BCOR-CCNB3 sarcomas and an epithelioid cell component in two CIC-associated sarcomas (one CIC-DUX4-positive and one CIC-DUX4-negative sarcomas). Mitotic activity was low in both heterogeneous components. By immunohistochemistry, in seven BCOR-CCNB3 sarcomas expression of EMA was positive in two cases, of p63 in three, of CD56 in six, of TLE1 in seven, of NKX2.2 in two, of CCNB3 in seven, and of BCOR in six cases (one case could not be tested for BCOR). In nine cases of CIC-associated sarcoma, CD56 was expressed in five, alpha-smooth muscle actin in one, ERG in three, and CD99, WT1 and TLE1 each in eight cases. Both sarcoma types showed not only a small round cell component, but also a myxoid/epithelioid component with low mitotic activity.

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