Abstract-ZnO nano-rods grown by gaseous-disperse synthesis (GDS) are confirmed by XRD analysis to have the wurtzite crystal structure. The obtained crystallites, as found from SEM studies, are 57±9 nm in diameter and 470±30 nm long on the average. Two emission bands of photoluminescence from ZnO nano-rods observed at room temperature are centered at 376 nm and 520 nm. A bio-sensitive layer is prepared by immobilization of Anti-Salmonella antibodies (Ab) from liquid solutions on the ZnO surface. Immobilization of the bio-sensitive layer onto ZnO nano-rods is found to increase the intensity of PL. After further reaction with Salmonella antigens (Ag) the PL intensity is found to decrease proportional to antigen concentrations in the range of 1000 -1000000 cell/ml. The possible mechanism of biosensor response is suggested and discussed.

The radiative characteristics of the condensed phase in the combustion zone of a laminar diffusion aluminum particle flame were studied by spectral methods. It is shown that the weak dependence of the condensed-phase temperature on the mass concentration of the fuel was due to heat losses, which increased strongly with increasing mass concentration and reached 20% of the total heat release. Strong temperature dependence of the imaginary part of the complex refractive index was obtained, which ultimately limited the flame front temperature. In practice, this should lead to a dependence of the heat losses on the condensed phase temperature stronger than T 4 . The dependence of the imaginary part of the complex refractive index on the wavelength was determined experimentally at the combustion temperature.

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Using photoluminescent ZnO nanorods and carbohydrate marker SSEA-4, a novel cancer cell recognition system was developed. Immobilization of SSEA-4 antibodies (αSSEA-4) on ZnO nanorods was performed in buffer solution (pH = 7.1) over 2 h. The cancer cell line probes were fixed on the glass slide. One hundred microliters of ZnO-αSSEA-4 conjugates were deposited on the cell probe and exposed for 30 min. After washing photoluminescence spectra were recorded. Based on the developed methodology, ZnO-αSSEA-4 probes were tested on patient-derived breast and colorectal carcinoma cells. Our data clearly show that the carbohydrate SSEA-4 molecule is expressed on cancer cell lines and patient-derived cancer cells. Moreover, SSEA-4 targeted ZnO nanorods bind to the patient-derived cancer cells with high selectivity and the photoluminescence signal increased tremendously compared to the signal from the control samples. Furthermore, the photoluminescence intensity increase correlated with the extent of malignancy in the target cell population. A novel portable bioanalytical system, based on optical ZnO nanorods and fiber optic detection system was developed. We propose that carbohydrate SSEA-4 specific ZnO nanorods could be used for the development of cancer diagnostic biosensors and for targeted therapy.