The eight‐coordinate lanthanoid complexes (I) are prepared by 1:3 molar reaction of corresponding lanthanoid chlorides with the Schiff bases from sulfamethoxazole and salicylaldehyde or thiophene‐2‐aldehyde in ethanol.
Lycofolinc for111s a monoacetyl or a diacetyl derivative, depending on the reaction conditions. Hydrogenation of lycofoline yields dihydrolycofoline. Sodiun~ borohydride reduction of acrifoline under non-epinlerizing conditio~ls gives the known acrifolinol, but reduction in the presence of sodium hydroxicle gives both acrifolinol and lycofoline. From these reactions as well as the evidence of n.m.r. spectra, lycofoline is shown t o have s t r u c t~~r e IV.The allcaloid lycofoline, C1,jI-I?502N, 1n.p 144-145O, [aID -75O, was isolated recently by Anet and I
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