Objective: To evaluate the impact of Early Start, an obstetric clinic-based prenatal substance abuse treatment program, on perinatal outcomes. Result: SAT women had either similar or slightly higher rates than the control women on most outcomes but significantly lower rates than S women. SA women generally had intermediate rates to the SAT and S groups. In multivariate analysis, the S group had significantly worse outcomes than the SAT group: preterm delivery (odds ratio (OR) ¼ 2.1, 1.3 to 3.2), placental abruption (OR ¼ 6.8, 3.0 to 15.5) and IUFD (OR ¼ 16.2, 6.0 to 43.8).Conclusion: Substance abuse treatment integrated with prenatal visits was associated with a positive effect on maternal and newborn health.
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