Cardiovascular disease is a major cause of morbidity and mortality in Type II (non-insulin-dependent) diabetes mellitus. Most of the patients die from cardiovascular complications, particularly from ischaemic heart disease [1±3].The mechanisms responsible for the increased cardiovascular risk in Type II diabetes are not fully understood. Diabetes is associated with many well-established cardiovascular risk factors. Patients with Type II diabetes have characteristic lipid abnormalities related to insulin resistance, i. e. hypertriglyceridaemia and low . The Paris Prospective Study [7] showed that hypertriglyceridaemia is an independent cardiovascular risk factor among Type II diabetic patients.A new lipoprotein classification was established more than 10 years ago by Alaupovic, Puchois and Fruchart, depending on apolipoprotein composition, which accounts for their functional specificity [8].Among triglyceride-rich lipoproteins, the ªEtude cas-tØmoin sur l'infarctus du myocardeº (ECTIM) Study [9,10] emphasised the important role of Lp B:C3 in the occurrence of myocardial infarction in non-diabetic patients.There have been no studies reporting the relation between such lipoproteins and macrovascular disease or cardiovascular mortality in patients with Type II diabetes.The purpose of this study was to assess relations between triglycerides, apo C3, Lp B:C3 and macroangiopathy, especially coronary heart disease in patients with Type II diabetes. Diabetologia (2000)

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