Objective: To estimate neonatal health benefits and healthcare provider costs of a theoretical Group B streptococcal (GBS) hexavalent maternal vaccination programme in The Gambia, a low-income setting in West Africa.Methods: A static decision analytic cost-effectiveness model was developed from the healthcare provider perspective. Demographic data and acute care costs were available from studies in the Gambia undertaken in 2012-2015. Further model parameters were taken from United Nations and World Health Organisation sources, supplemented by data from a global systematic review of GBS and literature searches. As vaccine efficacy is not known, we simulated vaccine efficacy estimates of 50-90%. Costs are reported un US dollars.
HighlightsAn updated epidemiological teaching exercise was developed.Students participate in an outbreak that they subsequently analyse.Data from five years of consecutive student cohorts is presented.An R package and practical are developed that improve the pedagogical experience.
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