Nowadays people are becoming poisoned through the consumption of herbal remedies that comprise heavy metals (HMs) worldwide. It is possible for HMs to be present in pharmaceutical herb materials coming from anthropogenic activities like agriculture, industrial waste, and natural sources. In various ethnic groups, there is evidence that contaminants were purposefully added in the belief that they had some sort of therapeutic benefit. HM toxicity of medicinal plant products has been linked to a wide range of adverse health effects, causing dysfunction of the liver, kidney, and heart, and even death. Natural plant-based products established around the world have progressed to the point that they now combine a variety of synthetic products for their purported medical benefits. This assessment focuses on the impacts of HMs on plants, sources of HMs, herbal sample collection, and identification techniques, especially in medicinal plant samples. At the same time, it focuses on the sociocultural applications of HMs as well as the dangers associated with their usage in conventional therapies. It is necessary to implement appropriate regulation and monitoring systems for natural supplements due to the prevalence of hazardous HMs.
It was found that the fruits of Sorbus aucuparia and Sorbus intermedia , growing in Donbas, contain significant amounts of flavonoids, ascorbic, free organic and oxycinnamic acids and exhibit high antioxidant activity, which proves their value in medical practice. It has been established that increasing the degree of technogenic pollution causes a decrease in the amount of flavonoids, tannins, carotenoids, ascorbic, free organic and oxycinnamic acids and an increase in the content of anthocyanins in the studied raw material. Ecological safety of raw materials was estimated.
The influence of technogenic pollution on the dynamics of the content of biologically active substances and the antioxidant activity of the previously poorly studied species Rosa lupulina Dubovik was studied for the first time. The compliance of R. lupulina fruits growing in the Donbas with the requirements of regulatory documentation was evaluated. The relationship between the content of heavy metals (lead, cadmium, mercury) in the fruits of R. lupulina and the soil on which they grow was studied. The environmental safety of raw materials was evaluated.
Представлены результаты количественного определения некоторых групп биологически активных веществ (флавоноидов, дубильных веществ и аскорбиновой кислоты) в листьях Crataegus fallacina Klokov растений, произрастающих на участках с различной степенью техногенного загрязнения. Оценено соответствие листьев C. fallacina, собранных на территории Донецкого региона, требованиям Европейской фармакопеи по содержанию действующих веществ.
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