Introduction: Allergic rhinitis is one of the most common allergic diseases, characterized by the infl ammation of the nasal mucosa. Eosinophils play a predominant pro-infl ammatory role in allergic infl ammation. This study assesses the effect of mometasone furoate alone or in combination with desloratadine/montelukast in patients with moderate-severe allergic rhinitis. Material and method: This is a prospective study that took place over 8 weeks on 70 patients diagnosed with moderate-severe allergic rhinitis with sensitization to the pollen of Ambrosia elatior. The patients were evaluated on the basis of their symptoms using the total score of nasal symptoms, the score of individual nasal symptoms and the number of eosinophils in the nasal secretion. Results: All 3 groups of patients had an improvement on the total nasal symptoms score. However, the combination of mometasone furoate with desloratadine provided statistically signifi cant benefi ts on the total score of symptoms and on nasal itching as compared with mometasone furoate alone.
Conclusions:The association of mometasone furoate with desloratadine should be considered fi rst-line treatment of moderate-severe allergic rhinitis due to the benefi t both on the total symptom score and on of nasal itching.
Background:The casein is the main protein that appears to be involved in childhood diseases caused by the consumption of adapted infant-milk formula (IMF).
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