The purpose was to study the parameters of induced blood oxidation (IOC) during myocardial revascularization in the conditions of artificial circulation and on the beating heart. Material and methods. The study included 64 patients who underwent coronary bypass surgery, including 31 (48.4%) On-pump patients and 33 (51.6%) Off-pump patients. Oxidative stress simulations were conducted under in vitro conditions. Blood oxidation induced values were studied using a biological oxygen monitor. Results. In patients with CHD, regardless of the choice of the revascularization method (On-pump/Off-pump), higher values of the initial and maximum rate of blood oxidation, the coefficient of oxidative activity and a shorter initiation period were observed statistically significantly (p0.05). No significant differences were observed in the inter-group comparison analysis at both 10 days and 6 months post-surgery. Conclusion. The parameters of induced blood oxidation do not depend on the method of revascularization: coronary bypass grafting in artificial circulation or on a beating heart. Changes in parameters indicating activation of the oxidative and antioxidant blood systems may be transient in nature and occur in the early postoperative period.
Coronary heart disease (CHD), being one of the most common cardiovascular diseases, has a negative impact on patients’ quality of life. The purpose of the work was to study the dynamics of quality of life indicators in patients with CHD during surgical revascularization of myocardium depending on the presence or absence of old myocardial infarction. 68 patients with CHD were examined, including 57 (83.8%) patients with old myocardial infarction (old MI) and 11 (16.2%) patients in the absence of old MI. There was a statistically significant improvement in quality of life, both in the physical and psychoemotional spheres, in patients with stable coronary heart disease including those with a history of myocardial infarction. No effect of old MI on quality of life in patients after myocardial revascularization surgery was observed.
Coronary heart disease (CHD), being one of the most common cardiovascular diseases, has a negative impact on patients’ quality of life. The purpose of the work was to study the dynamics of quality of life indicators in patients with CHD during surgical revascularization of myocardium depending on the presence or absence of old myocardial infarction. 68 patients with CHD were examined, including 57 (83.8%) patients with old myocardial infarction (old MI) and 11 (16.2%) patients in the absence of old MI. There was a statistically significant improvement in quality of life, both in the physical and psychoemotional spheres, in patients with stable coronary heart disease including those with a history of myocardial infarction. No effect of old MI on quality of life in patients after myocardial revascularization surgery was observed.
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