Cervical cancer is considered the fourth most common malignancy and the fifth fatal cancer in women, oncogenic Human papillomavirus are considered a primary cause of development of cervical cancer. It has also been suggested that viral coexistence may also accelerate the progression of cervical lesions to cervical cancer. This study aims to study the coinfection of Epstein Bar, Herpesvirus 8 and Hepes simplex type 2 infections in women with cervical cancer with the presence of Human papillomavirus and their correlations with the clinicopathologic characteristics of patients. In this study, 73 samples that tested positive for Human papillomavirus in previous study were used for the detection of Epstein Bar, Herpesvirus 8 and Hepes simplex type 2 in tumor tissue using Polymerase Chain Reaction techniques, and the clinical relevance was analyzed statistically. Of the 73 samples (48%) were infected with Epstein Bar, (24.65%) infected with Herpesvirus 8 However, none of the cases were infected with Hepes simplex type 2. The frequency of co-infections was 16.43% of cases. No significant association was found between co-infection and other clinicopathologic features. Therefore, these results represent arguments in favor of the role of Epstein Bar and Herpesvirus 8 among Human papillomavirus positive cases, as potential cofactors in cervical carcinogenesis, which could lead us to develop new therapeutics and preventive vaccines.

In Morocco, cervical cancer and precancerous lesions are still a public health problem and many efforts are made to improve women's awareness on Human papillomavirus (HPV) infection and methods preventing its dissemination. This study was planned to evaluate HPV prevalence and to assess the predominant HPV genotypes circulating in Morocco. A total of 360 women, attending caravans of sensitization and screening for cervical lesions were recruited from 9 different regions of Morocco. Socio-demographic, familial and medical data of participating women were recorded. HPV testing and genotyping were performed by Polymerase Chain Reaction and DNA direct sequencing. The overall HPV prevalence was 30.28% of the recruited women. Of the positive samples, 61.46% were infected with a high-risk HPV genotype, whereas 38.54% showed a low-risk HPV genotype. The most prevalent high-risk HPV genotypes were HPV 16, 59, and 18 with a prevalence of 25.68, 11.92 and 8.25%,

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Introduction : Quality of life (QOL) has become an important part of the medical decision along with the efficacy and safety of treatment. Cancer is a chronic disease that affects the quality of life of patients from which the idea of evaluating the QOL of patients treated in the service. This is a descriptive cross-sectional study carried out at the Mohamed VI center for the treatment of cancers of Ibn Rochd Hospital of Casablanca over a period of one year. Results : In our study, the QOL was evaluated by the Moroccan Arabic dialect version adapted and validated to our context of the survey (FACT), the servey is divided into 5 modules (localization of the cancer): breast, cervix, endometrium, ovary and vulva . Based on the results of this study, we can conclude that the localization of the cancer does not affect the QOL of the patients, besides the concept of the quality of life of the cancer patients is a primordial element, and useful for the choice of the patients therapeutic decisions, the evaluation of the different anticancer treatments and still for the rehabilitation of the patients with cancer.

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