BackgroundEssential micronutrients are important for maintenance of life. Deficiency of micronutrients is more likely to be encountered in children, and women studies are required to investigate the status of micronutrients in children and women. This study aimed to longitudinally evaluate changes in zinc, copper, and iron levels in breastfed infants and their mothers during the first year of life.MethodsSerum and hair samples were obtained from 35 healthy breastfed infants (51 % males, 49 % females) and their mothers 2, 6, and 12 months after delivery. All of the samples were assessed using an atomic absorption spectrophotometer. Serum iron levels were determined by a Roche/Hitachi/Modular analyzer. Statistical analyses were performed using SPSS-PC (Version 21.00) software.ResultsHair zinc (p < 0.05) and serum iron (p < 0.001) levels of infants were significantly decreased towards the end of the first year. Infants’ serum copper levels were increased towards the end of the first year. Maternal serum and hair copper levels and serum iron levels were significantly decreased towards the end of the first year. There were no significant correlations between dietary zinc, copper, iron intake, and trace element levels of infants and their mothers.ConclusionsInfants’ hair zinc levels, maternal and infants’ hair copper levels, and infants’ and maternal serum iron levels declined towards the end of the first year. Infants need more zinc after 6 months of age. Infants’ and mothers’ daily iron intake was less than the recommended intake.

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Serum vitamin D levels in children with obesity with hepatosteatosis are significantly lower than vitamin D levels in children with obesity without hepatosteatosis. In this observational study we only refer to the association of vitamin D deficiency/insufficiency with hepatosteatosis.

Brucellosis is considered the most widespread zoonosis in the world. In endemic regions of brucellosis, childhood brucellosis includes up to one-third of all cases of human brucellosis. Brucellosis constitutes a public health problem in Turkey. A boy aged 12 yr who had PFIC2 had undergone deceased-donor liver transplantation in 2008 at the age of seven. The boy presented with fatigue, fever, and pain in the right leg and hip and was admitted to the hospital. Brucella melitensis grew in the blood culture, and the SAT was positive at a titer of 1:640. The patient was treated with oral doxycycline and rifampicin for eight wk. After treatment, the patient recovered and his blood cultures became negative. The patient's mother also had a high Brucella agglutination titer of 1:320 positive and was treated in the internal medicine department with spiramycin and doxycycline. Brucella infection should be suspected in liver transplant recipients with fever of unknown origin, especially in recipients who live in an endemic area.

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Amaç: Çocukiuk döneminde perkutan endoskopik gastrostomi i §lemi yapilan olgularin demografik bulgufarini degerlendirmek. Gereç ve Yöntem: Çali §maya 2005-2012 arasinda endoskopi birimimizde perkutan endoskopik gastrostomi i §lemi uygulanan oigular alinmiçtir. Olgularin demografik bulguiari, hasta dosyalarindan elde edilmi § ve geriye dönük olarak incelenmiçtir. Bulgular: Çaliçma grubumuzda yedi sene içinde 104 olguya (46 kiz, %44), 269 perkutan endoskopik gastrostomi ve perkutan endoskopik gastrostomi ili §kili i §lem gerçekle §tirilmi §ti. Ortaiama izlem süresi 36,5 aydi (3-84 ay). Perkutan endoskopik gastrostomi i §lemi uygulanmi § olgularm çogunlugunu nörolojik ve metaboiik hastaliklari olan oigular olu §turmaktaydi (sirasiyla %45 ve %40). Perkutan endoskopik gastrostomi i §iemi uyguianmi? olgularda ortanca ya § 5,9 (2 ay -16 ya §), ortaiama tarti 17,7 kg (3-47 kg) idi. Olgularm i §lem öncesi tarti Z skoru ortanca degeri -1,98 olarak hesapfandi. Kirk be § oigunun i §lem sonrasi ortaiama on sekizinci ayda ortanca Z skor degeri 1,21 olarak bulundu (p=0,0007). Önemli komplikasyon üc olguda (%2,8), hafif kompiikasyon tüm i §lemler arasinda %10 siklikta saptanmifti. i §leme bagli eilt komplikasyonu sikligi %12,5 (n=13) idi. En sik görüien eilt komplikasyonu yerel stoma enfeksiyonuydu (7/13). Çali §ma grubumuzdaki hastalarda sistemik enfeksiyon gözlenmemi §tir. Çikarimlar: Bir çok ülkeden bildirilen olgu serilerinden farkli olarak ülkemizde perkutan endoskopi gastrostomi gereksinimi olan çocukiar arasmda metaboiik hastaligi bulunanlarm sikligi dikkati çekmektedir. Komplikasyonlarm görülmesine karçilik, perkutan endoskopik gastrostomi i §lemi, çocukiuk çaginda beslenmenin saglanmasmda güvenilir bir y öntemdir (Turk PedAr § 2013; 48; 210-4) Anahtar sözcükler: Çocuk, demografik bulgular, perkutan endoskopik gastrostomi Summary Aim: The aim of this study was to evaluate demographic findings of 104 children who had percutaneous endoscopie gastrostomy insertion procedure. Material and Method: Children, who had undergone PEG insertion procedure between 2005 and 2012 have been included in the study. Demographic data has been collected retrospectively from the clinic charts. Results: A hundred and four patients (44 girls, 46%) with 269 percutaneous endoscopie gastrostomy and percutaneous gastrostomy related procedures in the last seven years were enrolled in this study Mean follow-up time was 36.5 months (3-84 months). Patients with neurological disabilities and metabolic diseases constituted the majority (45% and 40% respectively). Median age of patients with percutaneous endoscopie gastrostomy proeedure was 5.9 years (2 months-16 years), mean weight was 17.7 kg ( 3-47 kg). Median Z score before PEG proeedure was -1.98. Follow-up weight Z seores were available for 45 patients. Follow-up Z score was 1.21 at a mean of 18 months after the PEG procedure (p=0.0007). Major complication was seen in three patients (%2.8). Minor complications were observed in 10% of all procedures. Skin complications were seen in 13 patients (12...

Summary Background: Crohn’s disease (CD) and ulcerative colitis (UC) are the two major relapsing conditions of inflammatory bowel diseases. Case Report: A case of Crohn’s disease with orofacial manifestations in a 10 year old girl is described. She had suffered from fever, dysphagia, arthralgia, painful recurrent ulcers of the oral mucosa and swelling of the lower lip lasting over 6 weeks. Clinical examination and the punch biopsy from the buccal mucosa revealed major recurrent aphthous ulcerations. A partial regression and significant relief of lesions were achieved two weeks after the treatment, but the patient suffered from abdominal pain, irregular bowel movements, arthritis, multiple hyperplastic and swollen mucosal folds, after 3 months. The patient was referred to a pediatric gastroenterologist. Esophagogastroduodenoscopy showed pyloric ulcer formation. Abdominal ultrasound showed increased thickening of the ileal wall with multiple enlarged lympadenopathies in the periileal region. Colonoscopy images showed deep ulcers with surrounding erythema. The histopathological examination of biopsies from the terminal ileum and the colon showed basal plasmacytosis, minimal crypt distortions and aphthous ulcerations. The diagnosis of Orofacial Crohn’s disease was made. Exclusive enteral nutrition for 8 weeks, followed by azathiopurine treatment was started with an excellent clinical response on abdominal and oral symptoms. Conclusion: Diagnosis of the disease by dentists and other clinicians through the evaluation of oral clinical findings is very rare. Mucocutaneous and granulomatous lesions of the oral cavity should alert the clinician to pursue an underlying systemic cause. Early communication with a gastroenterologist can help early diagnosis of Crohn’s disease for better patient management and prognosis.

Karaciğer nakil alıcılarında nakil öncesi ve sonrası dosya kayıtlarından anemi sıklığı, etiyolojisi ve klinik önemi araştırıldı.