Background: Partial arhinia is an extremely rare congenital malformation with an unclear pathogenesis. In this condition, the external nasal structures and nasal passages are absent, and it can be associated with somatic anomalies, other craniofacial abnormalities, severe feeding, and airway compromise. Objective: In this article, we describe a case of a baby born with congenital partial arhinia at Prince Rashid AlHasan Hospital in Irbid, Jordan. Case presentation: Her condition was associated with microcephaly, hypotelorism, cleft palate, microphthalmia, and micrognathia. The baby was the result of an unplanned pregnancy; the mother had received a Zoladex implant 2 months before the pregnancy as a treatment for endometriosis. Conclusion: Congenital partial arhinia could be associated with dangerous life-threatening complications such as feeding and airway compromise. Management of the condition is essential and urgent, including surgical correction as needed by a highly skilled team.
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