Medication non-adherence is a prevalent, complex problem. Failure to follow medication schedules may lead to major health complications, including death. Proper medication adherence is thus required in order to gain the greatest possible drug benefit during a patient's treatment. Interventions have been proven to improve medication adherence if deviations are detected. This review focuses on recent advances in the field of technology-based medication adherence approaches and pays particular attention to their technical monitoring aspects. The taxonomy space of this review spans multiple techniques including sensor systems, proximity sensing, vision systems, and combinations of these. As each technique has unique advantages and limitations, this work describes their trade-offs in accuracy, energy consumption, acceptability and user's comfort, and user authentication.

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In this paper, we describe and analyze a time-series dataset from toothbrushing activity using brush-attached and wearable sensors. The data was collected from 17 participants when they brushed their teeth over one week in 5 different locations. The dataset consists of 62 toothbrushing sessions for each of the brush-attached and wearable sensor approaches, using both electric and manual brushes. The average duration of each session is 2 minutes. One sensor device was attached to the handle of the brush while the other was worn by the participants as a wrist-watch. We collected the data from a 3-axis accelerometer and a 3-axis gyroscope at a 200 Hz sampling rate. Most of the data has been labelled. We investigated the characteristics of the data using spectral analysis and performed a pre-processing pipeline in order to generate features used to train a Support Vector Machine Classifier. We were able to identify which part of the jaw was being brushed with 98.6% accuracy. CCS CONCEPTS • Information systems → Data mining; • Computer systems organization → Embedded and cyber-physical systems; • Theory of computation → Machine learning theory.