Species of the genus Artemisia are well known for their use as ingredients in ancient medicine. The advantage of using plant extracts compared to individual pharmaceutical ingredients is the rate of adaptation of the pathogenic microorganisms to the drug. Due to the rapid development of multidrug-resistance in microorganisms in the field, it is essential to search for novel, effective drugs with low toxicity. Therefore, the purpose of this study was to isolate and study the biologically active substances obtained from various substances in the raw materials of Artemisia cina Berg. The identification of the main biologically active components was performed using the method of chromato-mass spectrometry. Moreover, the antiviral activity of several extracts was studied using the method of measuring limiting dilutions (the Reed–Mench method), with some modifications. For the first time, the biological activity of extracts from the raw material of Artemisia cina Berg. upon the SARS-CoV-2 virus was confirmed. All the obtained extracts exhibited nontoxic effects in animals, with an LD50 greater than 2 g/kg. Comprehensive toxicological analyses are also presented in the study, such as those of the biochemical parameters of urine after one day and one week of the extracts’ administration in mice at a dose of 2 g/kg body weight. In all groups of animals that received extracts of Artemisia cina Berg., a slight increase in the presence of red blood cells in their urine was observed one day following the administration of the extracts. This increase decreased somewhat after a week; however, it remained higher than the levels observed in the control animals. In the three groups, there was also a slight increase in the amount of ketones in the urine. Two weeks following the administration of the extracts to these groups, the internal organs of the animals were examined. The examination showed that the internal organs of the animals that received the extracts were not visibly different from those of the control animals in terms of their size or appearance. The weight of the internal organs of the animals that received the extracts was also similar to the weight of the internal organs of the control animals, illustrating the absence of toxicity.
In this paper, we developed the conditions for the deposition of zirconium oxide coatings from solutions containing hexafluorozirconic acid, nickel and molybdenum salts on a steel base. Optimal concentrations of nickel and molybdenum were determined to obtain oxide-zirconium coatings used as adsorption layers for paint coatings. The effect of temperature, time and subse-quent heat treatment on the protective anticorrosive and adhesive characteristics of oxide-zirconium coatings has been established. It is shown that the formed oxide-zirconium coating are nano scale size. It is established that the corrosion resistance of the investigated coatings in the temperature range 30-40°C is in agreement with their adhesion strength. On the basis of electro-chemical studies, it was shown that the addition of hexafluorozirconic acid to nickel and molybdenum salts leads to inhibition of iron ionization and an increase in the corrosion resistance of the formed coating.
A relationship between the adsorption capacity of 2,2 / -dipyridyl, 4,4 / -dipyridyl heterocyclic amines, 1,10-phenanthrolin and Fe (dipy) 3 2+ complex on mercury with the corrosive activity of these compounds on the iron electrode by cyclic voltammetry was established. The use of this method made it possible to establish a regularity between the process of the iron electrode ionization and the appearance of a current maximum due to the electroreduction of corrosion products on the cathode volt-ampere curves. It was found that 4,4 / -dipyridyl, isomer of 2,2 / -dipyridyl, has a stronger interaction of π-electrons with the surface of mercury and a flat arrangement on the surface of the electrode, which contributes to its more corrosive activity. It should be noted that 4,4 / -dipyridyl is able to form polymer low solubility compounds with metal ions, whereas 2,2 / -dipyridyl and 1,10-phenanthroline form chelate soluble complexes with Fe (II). Unlike molecules of 2,2 / -dipyridyl, which inhibit corrosion processes, complex compounds Fe (dipy) 3 2+ , being corrosion products, lead to increased corrosion.
NAS RK is pleased to announce that News of NAS RK. Series of geology and technical sciences scientific journal has been accepted for indexing in the Emerging Sources Citation Index, a new edition of Web of Science. Content in this index is under consideration by Clarivate Analytics to be accepted in the Science Citation Index Expanded, the Social Sciences Citation Index, and the Arts & Humanities Citation Index. The quality and depth of content Web of Science offers to researchers, authors, publishers, and institutions sets it apart from other research databases. The inclusion of News of NAS RK. Series of geology and technical sciences in the Emerging Sources Citation Index demonstrates our dedication to providing the most relevant and influential content of geology and engineering sciences to our community. Қазақстан Республикасы Ұлттық ғылым академиясы "ҚР ҰҒА Хабарлары. Геология жəне техникалық ғылымдар сериясы" ғылыми журналының Web of Science-тің жаңаланған нұсқасы Emerging Sources Citation Index-те индекстелуге қабылданғанын хабарлайды. Бұл индекстелу барысында Clarivate Analytics компаниясы журналды одан əрі the Science Citation Index Expanded, the Social Sciences Citation Index жəне the Arts & Humanities Citation Index-ке қабылдау мəселесін қарастыруда. Webof Science зерттеушілер, авторлар, баспашылар мен мекемелерге контент тереңдігі мен сапасын ұсынады. ҚР ҰҒА Хабарлары. Геология жəне техникалық ғылымдар сериясы Emerging Sources Citation Index-ке енуі біздің қоғамдастық үшін ең өзекті жəне беделді геология жəне техникалық ғылымдар бойынша контентке адалдығымызды білдіреді. НАН РК сообщает, что научный журнал «Известия НАН РК. Серия геологии и технических наук» был принят для индексирования в Emerging Sources Citation Index, обновленной версии Web of Science. Содержание в этом индексировании находится в стадии рассмотрения компанией Clarivate Analytics для дальнейшего принятия журнала в the Science Citation Index Expanded, the Social Sciences Citation Index и the Arts & Humanities Citation Index. Web of Science предлагает качество и глубину контента для исследователей, авторов, издателей и учреждений. Включение Известия НАН РК. Серия геологии и технических наук в Emerging Sources Citation Index демонстрирует нашу приверженность к наиболее актуальному и влиятельному контенту по геологии и техническим наукам для нашего сообщества.
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