Extratympanic electrocochleography (ECochG) was performed on 37 patients referred to the Evoked Potential Clinic with suspected Ménière's disease. The patients were classified according to their hearing impairment and audiometric configuration. Click and tone-pip stimuli with tone frequencies of 1 and 4 kHz were presented at a rate of 10 per second. Amplitude, latency and general waveform characteristics of the summation potential (SP) and action potential (AP) were analysed for each averaged response with respect to the level and configuration of the hearing loss. The highest incidence of abnormal percentage SP was in patients with average hearing loss in the range of 40–64 dB HL using the click stimulus. In low tone hearing loss, hydrops was identified from an enhanced SP in significantly more patients using the click and 4 kHz tone-pip than the 1 kHz stimulus. Measurement of the width of the 1 kHz tone-pip response waveform was abnormal in some patients even though the click and 4 kHz responses were normal. The optimum stimulus for identification of hydrops from an enhanced SP is dependent on the level and configuration of the hearing loss.
Objective To investigate the usefulness of copeptin and S100B levels in the differentiation of central and peripheral vertigo. Methods Ninety patients were included in the study. Copeptin and S100B levels were measured using the enzyme-linked immunosorbent assay method. Results The time between symptom onset and presentation to the emergency department was longer in the patients diagnosed with central vertigo. S100B and copeptin levels were significantly higher in central vertigo patients. The confirmed cut-off value was 17 for the S100B level and 1.65 for the copeptin level. Conclusion Quick and reliable differentiation between central and peripheral vertigo is important to reduce the length of hospital stay of patients in the emergency department, and for patient comfort. S100B and copeptin levels are potential biomarkers in the differential diagnosis of central vertigo and peripheral vertigo for patients whose aetiology of vertigo cannot be differentially diagnosed with history-taking and physical examination.
Objective: We aimed to investigate suspected cases of mushroom poisoning that were admitted to the emergency department of a metropolitan education and research hospital. Material and Methods:Suspicious cases of mushroom poisoning and determined mushroom poisoning patients were investigated in the medical records of patients who were older than 18 years old in 1 year. We examined patient's demographic information, admission date, complaints, time of complaint starting, and clinical and laboratory findings. Treatments and results were evaluated. Results:We analyzed 74 patients who were diagnosed with mushroom poisoning. The most common complaints of the patients were nausea and vomiting. İn-creases in the number of admission were observed in November and December. A total of 25 patients were externed from emergency medicine, and 39 patients were hospitalized. 5 patients treatment with hemodialysis and both of them died. Conclusion:Mushroom poisoning is known to vary according to seasonal distribution, type of mushroom, geographic shape, and climate of the region. Therefore, emergency physicians should investigate the characteristics and ecology of the region and the geographic shape, so that provision services can facility the emergency departments principles working and organizated. The importance of regional characteristics is lost in a metropolitan hospital. (JAEM 2014; 13: 162-5)
The use of electrocochleography (ECochG) in the identification of endolymphatic hydrops in Menière's disease, using either trans-tympanic or extra-tympanic recording techniques, has become very popular. The presence of an enhanced summating potential (SP) component is considered to be a diagnostic indicator of hydrops. The response evoked by a click stimulus is widely used in this investigation. The aim of this study was to assess the value of tone-pip stimuli for measurement of the SP component in patients with suspected Menière's disease. Extra-tympanic ECochG was recorded from a surface electrode positioned on the postero-inferior quadrant of the ear canal close to the tympanic annulus. Forty patients referred to the Evoked Potentials Clinic at the Queen's Medical Centre were studied. The combined summating potential and action potential waveform (SP/AP) were recorded using click and tone-pip stimuli. The pips had tone frequencies of 1 and 4 kHz and all stimuli were presented with alternating phase at a repetition rate of 10 per second. The percentage SP (%SP), width and latency characteristics of the SP/AP waveform were calculated for each stimulus condition. There were four patients (10%) with an enhanced tone-pip %SP when the click %SP was within normal limits. Width measurement of the tone-pip waveform at the onset point of the response was abnormal in 13 patients (33%) when a similar measurement of the click-evoked response was normal. There were nine of these patients identified by an abnormal width measurement at the 50% amplitude point of the SP/AP waveform. Both tone-pip frequencies were required in order to identify all these abnormal measurements.(ABSTRACT TRUNCATED AT 250 WORDS)
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