<p>A novel
drug delivery system is described based on a PEG-dendritic copolymer functionalized with peripheral boronic acids, that self-assembles in the presence of
catechol to afford nanometric micelles with the ability to encapsulate
GEM. The simplicity of the method, with all equilibria (boronate
esterification, copolymer self-assemble, drug encapsulation) occurring
simultaneously, is compatible with a high tunability of the micelle properties (via
diol structure and the boronic acid-to-diol molar ratio).<br></p>
<p>A novel
drug delivery system is described based on a PEG-dendritic copolymer functionalized with peripheral boronic acids, that self-assembles in the presence of
catechol to afford nanometric micelles with the ability to encapsulate
GEM. The simplicity of the method, with all equilibria (boronate
esterification, copolymer self-assemble, drug encapsulation) occurring
simultaneously, is compatible with a high tunability of the micelle properties (via
diol structure and the boronic acid-to-diol molar ratio).<br></p>
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