It has been well documented that IBS is associated with multiple factors such as anxiety, depression, mental and psychological stress, analgesics, and food intake, but as of yet, no such association has been established with smoking. Furthermore, smoking has been implicated in other gastrointestinal disorders, such as ulcerative colitis and Crohn's disease.

ADD regime was better tolerated by the patients than EDD regime. Alternate day therapy, with or without vitamin D supplementation, may be used by the physicians for troublesome muscular complains.

No abstract