This study is focus on generalized power law model of blood flow in a stenosed bifurcated artery under the effect of different types of stenosis. Stenosis can cause the narrowing of the artery that may reduce the flow of blood supply to the heart, and this may lead to the heart attacks. The geometry of the bifurcated artery with different classification of stenosis locations is considered in order to shows four possible morphologies formation of plaque from healthy artery to disease artery. The bifurcated artery is modelled as a two-dimensional rigid wall since the wall of a disease artery is reported to be less flexibility. Few assumptions are considered such as blood are incompressible, laminar, steady and characterized as the generalized power-law model. Simulation results are obtained using COMSOL Multiphysics 5.2, which is a software that based on the finite element method to solve this problem. Results concerning the effect of different locations of stenosis on generalized power law model of the blood flow characteristic such as streamlines pattern are discussed.
The development and progression of stenosis with a high probability of rupture can be altered by changing the heat distribution in the bifurcated artery. The purpose of this study is to investigate the behavior of blood flow from healthy to unhealthy artery bifurcation under the influence of bioheat transfer. The blood flow is modelled as laminar, two-dimensional, steady, incompressible, and characterised as a Newtonian fluid. The Galerkin weighted residual (GWR) method is utilised to solve the governing equations. The behaviour of the blood flow due to different Reynolds numbers and the severity of stenosis is graphically investigated and discussed. The results reveal that the velocity profiles increase as the degrees of constriction increase. However, a lower Reynolds number enhances the axial velocity in an artery. The blood flow behaves differently from healthy to unhealthy on the bifurcated artery in the presence of an arterial constriction. The behaviour is significantly affected by the rate of heat transfer and the location of stenosis.
Localized plaque causes narrowing of the arterial wall, resulting in an alteration in the flow structure, reducing the flow of fluids reaching the heart and resulting in heart attacks. The formation of stenosis could disturb the normal hemodynamics in blood rheology. A bifurcated artery with different types of stenosis is considered in order to illustrate the four possible formations of plaque between healthy and diseased arteries. Due to the fact that a diseased artery is reported to be less compliant, the artery wall is modelled as a two-dimensional rigid wall. In this model, blood flow is assumed to be steady, laminar, incompressible, and characterized as a generalized power-law model that is non-Newtonian in nature. The numerical simulation is performed using COMSOL Multiphysics, which is based on finite element method. Based on simulation results, different types of stenosis in the bifurcated artery have a significant impact on velocity profiles and wall shear stresses.
Microfluidics devices offers reliable transport mechanism to drive fluid within a microscale flow. This research work aims to identify the characteristic of flow in valveless impedance pump which uses acoustic impedance mismatch to drive flow using numerical simulations. The focus of the studies is designing a well performed pump where the required displacement of elastic wall can still be achieved even when the force applied in different locations and also a mechanism that requires low input current. Shear rate resulting from the pumping mechanism were measured at different input boundary conditions. Important parameters such as pinch location can affect the direction of the velocity magnitude and shear rate. It is found that the maximum shear rate occurred at 2 mm pinch location at 400 s-1. Hence, the pump design from this study can be used as the best application for microfluidic systems where a high pumping amount is desired.
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