PurposeTo determine whether the measurement of serum AMH can be used to diagnose PCOS and as a tool to predict the prognosis of PCOS.MethodsThis is a case–control study. Women of reproductive age (18–35 years) were recruited consecutively at a tertiary academic hospital during the period of March 2009–October 2011 and were divided into case (PCOS patients defined by the Rotterdam criteria) and control groups (non-PCOS patients). Menstrual history, clinical manifestations of hyperandrogenism, ovarian ultrasound assessments, and the levels of AMH, LH, FSH, and estradiol were collected.ResultsSeventy-one cases and 71 controls were recruited. AMH serum levels were significantly higher in PCOS patients than in controls. The Area Under the Curve (AUC) of the serum AMH assay in PCOS patients reached a value of 0.870. With a cut-off value of 4.45 ng/ml, the serum AMH level had a sensitivity of 76.1 % and a specificity of 74.6 %. The most common phenotypes of PCOS in this study were anovulation and polycystic ovary (63.4 %). However, the mean level of AMH was highest in the phenotypes of anovulation, polycystic ovaries and hyperandrogenism (11.1 ng/ml).ConclusionsIn Indonesian women, AMH can be used as an alternative diagnostic criteria for PCOS patients with a cut-off value of 4.45 ng/ml. AMH value rise when hyperandrogenism is present therefore serum AMH levels also reflect the phenotype of PCOS. However, these findings must be confirmed with larger clinical studies.

BACKGROUND: As of January 2021, Indonesia had the 21st highest number of total COVID-19 cases and the 17th highest total deaths among all countries. COVID-19 infection in pregnant women seems to negatively affect both maternal and neonatal outcomes. CASE REPORT: We describe four cases of pregnant women confirmed with severe and critical COVID-19 that resulted in maternal death from November until December 2020. The first case was complicated with thrombocytopenia, her condition quickly deteriorated post-delivery. Pulmonary embolism was suspected as the cause of death. Second and third cases were complicated with preeclampsia, obesity, and advanced maternal age. Second case came in sepsis condition. Her SARS CoV-2 RTPCR swab test came out after her death. Third patient did not have COVID-19 symptoms at admission. She starts having symptoms on second day and was confirmed positive a day after. She falls in septic shock. Fourth patient has history of fever, cough, and dyspnea. She was confirmed positive on first day and her condition worsened, diagnosed with bacterial co-infection sepsis on day eight. All patients underwent cesarean section. CONCLUSION: Limited information and studies for COVID-19 management in pregnant women are challenging for obstetricians. Management should be individualized weighing the benefit and risks in presence of comorbidities or accompanying disease.

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The article titled “Consumer perspectives on reproductive health after using the Jakpros smart mobile health application: A cross-sectional, qualitative study” ([version 1; peer review: 1 not approved] F1000Research 2019, 8: 396 https://doi.org/10.12688/f1000research.17894.1) has been retracted by F1000Research on the grounds of scientific misconduct. On submission to F1000Research, all manuscripts undergo plagiarism checks as standard—this is detailed in our Originality policies. Upon submission, authors are also required to declare that the article is not under consideration or review by another publisher. At this stage in the publication process, our plagiarism detection software did not identify any significant duplication of text. Following publication of the article, the F1000Research editorial team were notified of a high degree of similarity between this manuscript and one already published in the Institute of Physics (IOP) Conference Series: Earth and Environmental Science (B Wiweko et al 2019 IOP Conf. Ser.: Earth Environ. Sci. 248 012038 https://iopscience.iop.org/article/10.1088/1755-1315/248/1/012038/pdf). On investigation, the extent of overlap between these two publications was substantial, and this was deemed a case of duplicate publication. Duplicate publication is a major ethical issue and, as a member of the Committee on Publication Ethics (COPE) and a follower of the International Committee of Medical Journal Editors (ICMJE) recommendations, F1000Research takes such matters seriously. In response to our concerns, corresponding author Budi Wiweko acknowledged that publication misconduct has taken place and has been informed that, due to the extent and nature of duplication between the articles published in F1000Research and IOP, F1000Research will retract the article and publish a linked retraction notice. In line with COPE guidelines, F1000Research has informed the Publisher of IOP Conference Series about this issue, and our final decision has been communicated to all authors and their respective institutions.

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Background:  Good reproductive health is important for individuals and also for the development of children. Knowledge plays an important role in women’s reproduction health. Our study examined women’s perspectives and knowledge of reproductive health after using the free Jakarta Reproduction Sehat (Jakpros) application (app) on a daily basis for two weeks. Methods: Our study used a cross-sectional, qualitative design. The sample consisted of 12 participants from two sub-district general hospitals in Jakarta. Participants were chosen using purposive sampling and consisted of women of reproductive age who had completed previous questionnaires on their use of Jakpros. We used descriptive analytics and a qualitative method. Data were collected by direct observation in small focus group discussions. Results: Participants said that after they used the Jakpros app, they were more aware of their reproductive health. Their knowledge increased after counselling combined with Jakpros usage. They also said that the features in the app made it easier to contact their doctor and to access their nearest hospital. Conclusion: Jakpros is a convenient way to access reliable reproductive health information.

Objective : Our study aimed to evaluate the perspectives of health care providers of JAKPROS ( Jakarta Reproduksi Sehat ) application that is used to improve the maternal health service. This descriptive qualitative study engaged 16 healthcare providers from two sub-district hospitals. The participants were selected using purposive sampling and cross-sectional design. Participant were asked to fill the written informed consent.Data were collected by in-depth discussion of a list of selected questions in a focus group discussion. Results: Most health care providers used paper-based systems in their hospitals.They said that it was very helpful in helping them communicate with their patients and provide information. The application has many benefits that help doctors provide the best service for patients during pregnancy.The use and adoption of app is needed to make a further improvements in the healthcare system. This study will help improve the application for more widespread use in a greater number of hospitals. JAKPROS made healthcare provider easier to communicate and track patient’s health. This app also assist patients related to the doctor’s schedule, health information, and nearest hospital.