Introduction: Origanum vulagre L. is known for its abundant essential oil content with monoterpene and sesquiterpene derivatives.
Aims: This research aims to gather comprehensive information about oregano and its potential to be developed into a nanotechnology drug delivery system.
Methods: Literary studies were conducted using data obtained by searching through online literature sources. Results: Oregano is reported to contain active phytochemicals like esitronellol. In modern scientific literature, its extracts have been reported to have antidiabetic, analgesic, anti-inflammatory, anticancer and other potential properties. Further research needs to be done to ascertain the safety and therapeutic effect of this plant. The development of oregano’s essential oil into nanoparticles in dosage forms can increase its solubility, stability, and pharmacological effects.
Introduction: One of plants that may have therapeutic potential is the Cymbopogon schoenanthus (L.) Spreng, also known as camel grass.
Aim: This review aims to investigate and gather comprehensive information about camel grass plants and their potential to be developed into a nanotechnology drug delivery system.
Methods: This review examined a variety of online literature.
Results: It was found that camel grass contains essential oil such as piperitone. Piperitone is efficacious as an antioxidant, antimicrobial and anti-inflammatory, in addition to other properties . The development of camel grass essential oil into lipid-based nanotechnology preparations can improve its bioavailability, solubility, and stability, thereby improving its potential effectiveness.
Ipomoea reptans Poir has many health benefits, such as decreasing blood glucose and as an antioxidant. Self-nano emulsifying drug delivery systems (SNEDDS) are an innovation in pharmaceutical technology that minimizes drug molecules and maximizes surface area, thus increasing drug absorption. This study aimed to investigate SNEDDS of I. reptans acute toxicity in female Wistar rats. An acute toxicity test was done using a limit test of OECD 423. Female Wistar rats were divided into control and treatment groups, with three animals for each group being used per step. No animals died after they were given SNEDDS of I. reptans leaves extract at a dose of 2000 mg/kg. No toxic effect was detected at clinical examination and histopathology of the organ. SNEDDS of I. reptans leaves extract had an LD50 cut-off value of 5000 mg/kg.
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