Objective: To compare the efficacy of zinc as an adjuvant therapy in the treatment of severe pneumonia in children between 2 months to 2 years of age. Study Design: Case Control study. Setting: Department of Paediatrics, Mayo Hospital Lahore. Period: 20 February 2019 to 20 August 2019. Material & Methods: After approval of Institutional Review board of King Edward Medical University Lahore Pakistan total 200 cases were selected by Consecutive (non probability) sampling and were divided into 2 groups each containing 100 cases. Group A children were given 20 mg elemental zinc per day plus Ampicillin plus cloxacillin while Group B patients were given only on Ampicillin plus cloxacillin. Mean + Standard deviation were calculated for continuous variables like age, base line zinc level and duration of fever. Post stratification chi square test was applied in which P value ≤0.05 will be considered as significant value. Results: Mean Age was recorded as 09 Months ± 5.54 in Group A while in Group B it was recorded as 12 Months ± 6.47. In Group A, 56 (56%) infants showed improvement who were administered zinc while 44 (44%) did not. Similarly, in Group B, 38 (38%) infant patients showed improvement who were not administered zinc whereas 62 (62%) did not show any improvement. This improvement was statistically significant P Value = 0.010. Conclusion: This study revealed a statistically significant efficacy estimate for zinc in the resolution of severe pneumonia.
Objective: To compare the open appendectomy with & without peritoneum closure in term of post-operative pain and operative time. Study Design: Comparative study. Setting: EAST Surgical Ward, MAYO Hospital Lahore, Pakistan. Period: July 2019 to June 2020. Material & Methods: Sample size of 150 patients were selected by consecutive non probability sampling technique. Patients were divided into 2 groups with 75 patients in each group. In Group A patients, peritoneum was closed while in Group B patients, peritoneum was not closed. The results of both groups were compared. Data was collected by pre designed proforma and evaluated by SPSS 26. Results: Out of total 150 patients, 96 (64%) were male and 54 (36%) were females. Most common age group was between 31 years to 40 years. The mean operation time taken by the patients in which peritoneum was closed was about 41 minutes with standard deviation of ± 10.54 minutes as compared to the Group B in which peritoneum was not closed and it took about 32 minutes with standard deviation of ± 6.22 minutes (P Value 0.025). On first post-operative day, mean pain experienced, by visual analogue score by Group A patients was 5.6 while 3.9 in Group B patients (P Value = 0.03). Conclusion: Non closure of peritoneum after open appendectomy reduces the operative surgery time and post-operative pain.
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