ABSTRAKCOVID-19 merupakan penyakit yang menginfeksi saluran pernapasan dan dapat ditularkan melalui droplet pada saat berbicara, batuk, dan bersin dari orang yang terinfeksi virus Corona. Pemahaman masyarakat tentang virus corona dapat diartikan sebagai hasil tahu masyarakat mengenai cara pencegahan, pengobatan dan komplikasinya. Poltekkes Kemenkes Palembang merupakan salah satu lembaga pendidikan tinggi yang berkewajiban menyelenggarakan Tridharma Perguruan Tinggi berupa kegiatan pengabdian kepada masyarakat pada Desa Mitra Poltekkes Palembang. Tujuan pengabdian masyarakat ini untuk meningkatkan pengetahuan masyarakat tentang Edukasi Kesehatan dan Penerapan Protokol Kesehatan Dalam Upaya Melawan COVID-19 serta membantu masyarakat beradaptasi di masa new normal. Metode dalam kegiatan pengabmas ini dengan memberikan penyuluhan kesehatan kepada masyarakat yang dilaksanakan di Posyandu Melati III Desa Lalang Sembawa. Kegiatan diikuti oleh 35 orang masyarakat desa. Kegiatan diawali dengan persiapan, pembagian leaflet, penjelasan materi dengan metode ceramah tanya jawab, diskusi dan evaluasi. Hasil dalam pengabdian masyarakat ini terdapat peningkatan pengetahuan dari 50% tingkat pengetahuan masyarakat menjadi 80% tingkat pengetahuan masyarakat Desa Lalang Sembawa yang paham mengenai Edukasi Kesehatan dan Penerapan Protokol Kesehatan Dalam Upaya Melawan COVID-19. Dapat disimpulkan bahwa kegiatan pengabmas ini dapat meningkatkan pengetahuan masyarakat tentang Edukasi Kesehatan dan Penerapan Protokol Kesehatan dalam Upaya Melawan COVID-19 serta membantu masyarakat beradaptasi di masa new normal. Kata Kunci : COVID-19; edukasi Kesehatan; protokol kesehatan. ABSTRACTCOVID-19 is a disease that infects the respiratory tract and can be transmitted through droplets when talking, coughing, and sneezing from people infected with the Coronavirus. Public Understanding of the coronavirus can be interpreted as the result of knowing the public about prevention, treatment, and complications. Poltekkes Kemenkes Palembang is one of the higher education institutions that is obliged to organize the Tridharma of Higher Education in the form of community service activities at the Palembang Poltekkes Partner Village. The purpose of this community service is to increase public knowledge about Health Education and Implementation of Health Protocols in Efforts to Fight COVID-19 and to help people adapt to the new normal. The method in this community service activity is to provide health education to the community which is carried out at the Melati III Posyandu, Lalang Sembawa Village. The activity was attended by 35 villagers. The activity begins with preparation, distribution of leaflets, explanation of material using question and answers lecture method, discussion, and evaluation. The results in this community service were an increase in knowledge from 50% of the community's knowledge level to 80% of the knowledge level of the Lalang Sembawa Village community who understood Health Education and Implementation of Health Protocols in Efforts to Fight COVID-19. It can be concluded that this community service activity can increase public knowledge about Health Education and Implementation of Health Protocols in Efforts to Fight COVID-19 and help people adapt to the new normal period. Keywords: COVID-19; health education; health protocol.
Carrots (Daucus carota), is the main sources of beta carotene besides tomatoes and palm oil. At present, β-carotene has been used extensively in food, industry, and medicine, so that beta carotene is of high economic value. The β-carotene in carrot can be obtained by chemical preparation. The researchers, usually to have βcarotene mainly done with organic solvents. It is very rarely done without a chemical solvent. This study aims to extract β-carotene without chemical solvent and also to determine β-carotene using UHPLC and GC-MS. Approximately 300 gram carrots, cleaned, cut into small pieces and mashed in a blender, given aqua 20 mL. separate the filtrate from that matrix. To the filtrate was then, added some chemical salt, centrifuged 5000 x g for 30 minutes to have pellet. The pellets are then removed, evaporated with the vacuum to dry at a temperature of 40o C for 48 hours. β-carotene pellets are measured with UV-vis, HPLC and GC-MS. Using column UHPLC and the mobile phase was chloroform-methanol (95: 5) with a flow rate of 1 ml /minute at a UV detector wavelength of 460 nm. The retention time examination of β-carotene and standard (sigma beta carotene) using HPLC and GC-MS was 3.75 and 9,80 minutes respectively. GC-MS examination showed ions and molecules of carotenoid. Research showed that this method can be used to be developed for the withdrawal of β-carotene in carrots and others, without any need for organic solvents.
Aromaterapi stik adalah modifikasi dari sediaan stik yang digunakan untuk terapi aromatik, seperti mengurangi stress. penggunaan asam sterat sebagai harding agent dapat menghasilkan sediaan stik yang baik dan stabil. Penelitian ini bertujuan untuk mengetahui konsentrasi asam stearat sebagai harding agent yang optimal untuk menghasilkan sediaan aromaterapi stik yang stabil dan memenuhi persyaratan. Aromaterapi stik dibuat menggunakan zat aktif campuran minyak lavender, jeruk manis dan bergamot yang berkhasiat sebagai aromaterapi. Penelitian ini menggunakan metode eksperimental, dengan campuran minyak sebagai zat aktif dan memvariasikan asam stearat sebagai harding agent. Pada formula I, II, III dengan asam stearat 18%, 19%, 20% dan 1% campuran minyak. Formula IV, V, VI dengan asam stearat 18%, 19%, 20% dan 2% campuran minyak. Kemudian dilakukan evaluasi sediaan selama 28 hari penyimpanan meliputi pH, suhu lebur, homogenitas, daya oles, warna, bau dan iritasi kulit. Hasil menunjukkan selama penyimpanan 28 hari sediaan aromaterapi stik memiliki pH yang cenderung meningkat, mengalami penurunan suhu lebur selama masa penyimpanan namun, masih masuk range suhu lebur sediaan stik 50°C-70°C dan semua sediaan aromaterapi stik memiliki daya oles yang baik, homogen dan tidak mengalami perubahan warna, bau serta tidak mengiritasi kulit. Campuran minyak lavender, jeruk manis dan bergamot dapat diformulasikan menjadi sediaan aromaterapi stik yang stabil dan memenuhi persyaratan. Formula paling optimal pada konsentrasi asam stearat 20% dan 1% campuran minyak.
Sediaan dry sirup kombinasi amoksisilin dan asam klavulanat merupakan obat pilihan pertama untuk pengobatan penyakit infeksi seperti pneumonia. Sediaan dry sirup kombinasi amoksisilin dan asam klavulanat merupakan sediaan antibiotik yang perlu disuspensikan terlebih dahulu sebelum digunakan. Suhu penyimpanan dan stabiltas zat aktif didalam sediaan sangatlah penting karena dengan adanya penambahan air didalam sediaan suspensi kombinasi amoksisilin dan asam klavulanat akan mempengaruhi degradasi kimiawi, fisik dan mikrobiologi. Penelitian ini bertujuan untuk mengukur adanya pengaruh suhu penyimpanan kombinasi amoksisilin dan asam klavulanat dalam sediaan dry sirup yang telah disuspensikan terhadap daya hambat bakteri Staphylococcus aureus. Jenis penelitian ini adalah penelitian eksperimental karena adanya perlakuan terhadap sediaan antibiotik kombinasi amoksisilin dan asam klavulanat yang dipengaruhi oleh suhu penyimpanan terhadap aktivitas antibakteri. Berdasarkan hasil pengukuran diameter daya hambat pada antibiotik suspensi kombinasi amoksisilin dan asam klavulanat pada penyimpanan hari ke-7 semua sampel suspensi dry sirup mengalami penurunan. Penurunan diameter zona hambat tertinggi terjadi pada sampel suspensi dry sirup generik yang disimpan pada suhu kamar. Dari hasil penelitian dapat disimpulkan bahwa adanya pengaruh suhu penyimpanan kombinasi amoksisilin dan asam klavulanat dalam sediaan dry sirup terhadap daya hambat bakteri Staphylococcus aureus dengan adanya penurunan daya hambat di akhir penyimpanan
In this study, pharmaceutical preparations for respiratory tablets in the form of patches have been developed, which are used by placing them on the skin, clothes or masks associated with the user. A patch formula containing a mixture of 3% ginger extract and ginger essential oil was created at 0.1%, 0.2% and 0.3%, respectively, with variations of PVA and PVP as polymers to control the release of ginger essential oil as a breathing reliever. Each preparation with ginger essential oil content used PVA and PVP with variations of 1:1, 1:1.5 and 1:2. The practices were evaluated for 21 days on days 0, 7, 14, and 21. TAfter obtaining long-lasting results, an irritation test was carried out on the respondents. The results showed that during storage for 21 days, the pH was in the range of 5.14-6.11, weight uniformity ranged from 1.24 g-1.65 g, humidity 7.18%-8.88%, and folding endurance >300 times. The variation of PVA and PVP shows that the higher the PVP content, the weight of the patch increases and the humidity decreases. So it can be concluded that a good formula is a formula with variations of PVA and PVP 1: 1.5 and ginger essential oil content of 0.3%. After obtaining long-lasting results, an irritation test was carried out on the respondents. The results showed that during storage for 21 days, the pH was in the range of 5.14-6.11, weight uniformity ranged from 1.24 g-1.65 g, humidity 7.18%-8.88%, and folding endurance >300 times. These alterations, do not change color and odor nor irritate the respiratory tract. The variation of PVA and PVP shows that the higher the PVP content, the weight of the patch increases, and the humidity decreases. So it can be concluded that a good formula is a formula with variations of PVA and PVP 1: 1.5 and ginger essential oil content of 0.3%; the weight of the patch increases, and the humidity decreases. So it can be concluded that a good formula is a formula with variations of PVA and PVP 1: 1.5 and ginger essential oil content of 0.3%.
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