Aim of the study was to determine the effectiveness and safety of intravaginal misoprostol VS intravenous oxytocin in induction of labour and to compare the induction delivery interval between prostaglandin induction and oxytocin induction and to detect maternal and foetal outcome between prostaglandin induction and oxytocin induction and also reduce the rate of caesarean section . A prospective, randomized trial was carried out in one hundred singleton pregnant women admitted in Dhaka National Medical Hospital during the period of January 2006 to December2006. Women who had unfavorable cervix (Bishop's score<) were selected. 50 of them received 50 mgm misoprostol intravaginally for three doses, 6 hourly. Another 50 patient received intravenous starting from 10 mU /ml up to 40mU.Thirty-nine patients out of 50 patients of misoprostol group achieved normal vaginal delivery. Rest eleven patients ended by caesarean section. 82% of this group delivered within 10 hours. The maximum required dose was 50-150mgm. Maternal complications were PPH 2% .Neonatal outcome were satisfactory. Thirty -six patients out of 50 patients of Oxytocin group achieved normal vaginal delivery. Rest fourteen patients ended by caesarean section. Only 66% of this group delivered within 10 hours. The maximum required dose was 40mU/ml. From the study it was found that intravaginal misoprostol is well tolerated and very effect then intravenous oxytocin in induction of labour in unfavorable cervix. It certainly reduces the number of caesarean section. It is cost effective. IntoductionInduction of labour is a standard obstetrics approach in properly selected patients. It is a method by which initiation of uterine contraction prior to their onset leading to cervical dilatation and effacement. A long induction delivery interval inevitably leads to important complications. Induction of labour should be simple, safe, effective and preferably non invasive. The success of induction depends to a large extend on the consistency, compliance and configuration of the cervix. The unripe cervix remains a well-recognized impediment to the successful induction of labour. A simple efficient method of ripening the cervix before induction is, therefore ,clearly of use. The main indications for medical induction of labour are PIH, Pre-eclampsia, diabetes in pregnancies Rhincompatibilities, APH, IUGR, IUD and others medical disorders in pregnancy.There are various methods by which labour may be induced with definite advantages and disadvantages, Among them prostaglandins are powerful agent Over the decades prostaglandins have been used locally quite frequently to effect cervical ripening and intravaginal, intracervical and extraamniotic routes have all been tried. Vaginal administration produce long lasting continuously increasing uterine contraction while no regular contractility could be seen in oral administration. It is apparent that a generation of obstetrician has practiced effective induction of labour by prostaglandin. Methods and MaterialsThis was a p...
Introduction: Hypertensive disorders are the commonest complications during pregnancy responsible for maternal and foetal mortality and morbidity. The aim of the study was to determine the magnitude of percentage of disorders in admitted pregnant women. A retrospective study was done to determine the pattern of disorders during pregnancy among the admitted pregnant women National Medical Institute Hospital. This study was done during January 2017 to December 2017 at Dhaka National Medical Institute Hospital. Materials and Methods: 3276 pregnant women admitted had medical disorders (406) with 12.39% at the age of reproduction (20-35 years). Results: The commonest disorders were hypertensive disease of pregnancy (45.32%), urinary tract infection (14.78%), gestational diabetic mellitus (10.84%), anaemia (7.39%), bronchial asthma (6.40%) respiratory infectious conditions (5.42%), viral infections (3.94%), thyroid disorder (3.45%), and cardiac disease (2.45%). Conclusion: Hypertensive disorder is the most common medical disorder of pregnancy followed by urinary tract infection, gestational diabetic mellitus, anaemia, bronchial asthma respiratory infectious conditions, viral infections, thyroid disorder and cardiac disease in order. Medicine Today 2020 Vol.32(2): 122-125
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