Synthesis of novel heterocycle systems: 6,8-dimethyl-2-(methylsulfanyl)-4-amino-substituted pyrimido[4′,5′:3,4]pyrazolo[1,5-a]pyrimidine and 9,11-dimethyl-5-(methylsulfanyl)pyrimido[2′,1′:5,1]pyrazolo[4,3-e][1,2,4] triazolo[4,3-c]pyrimidineThe novel heterocyclic pyrimidopyrazolopyrimidine system was synthesised through cyclisation of 4-hydrazinyl-2,6bis(methylthio)pyrimidine-5-carbonitrile with acetylacetone in high yield. Also, two other tetracyclic systems were synthesised through cyclisation of 4-hydrazinyl-6,8-dimethyl-2-(methylsulfanyl)pyrimido[4′,5′:3,4]pyrazolo[1,5-a]pyrimidine with triethyl orthoformate and sodium nitrite to obtain the pyrimidopyrazolotriazolo pyrimidine and pyrimidopyrazolotetrazolopyrimidine respectively.
Synthesis of Novel Heterocycle Systems: 6,8-Dimethyl-2-(methylsulfanyl)--4-amino-substituted Pyrimido[4',5':3,4]pyrazolo[1,5-a]pyrimidine and 9,11-Dimethyl-5-(methylsulfanyl)pyrimido[2',1':5,1]pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine. -Novel tri-and tetracyclic compounds based on pyrazolopyrimidine are synthesized starting from readily available 4-hydrazinylpyrimidine--5-carbonitrile (III). -(HASANPOUR, M.; ESHGHI*, H.; BAKAVOLI, M.; YUSEFI, M.; J. Chem. Res. 38 (2014) 11, 643-647, http://dx.doi.org/10.3184/174751914X14117992793459 ; Dep. Chem., Sch. Sci., Ferdowsi Univ., Mashhad 91775, Iran; Eng.) -H. Toeppel 23-193
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.