AimTo determine whether early clinical, laboratory and musculoskeletal ultrasound (MSUS) characteristics can be used as early detectors of juvenile idiopathic arthritis.Patients and methodsForty (40) patients with juvenile idiopathic arthritis (JIA) diagnosed according to the ILAR criteria [1] and 20 healthy control children. All patients were subjected to the following assessment at base line and at follow up after 6 months: Clinical evaluation, MSUS examination and laboratory evaluation.ResultsOf the 40 patients, 6 patients (15%) had systemic onset subtype, 8 (20%) oligoarticular extended, 9 (22.5%) oligoarticular persistent, 5 (12.5%) polyarticular rheumatoid factor (RF) +ve, 6 (15%) polyarticular RF −ve, 5 (12.5%) enthesitis related subtype and only one patient (2.5%) had psoriatic JIA. MSUS detected more synovitis than clinical examination (subclinical synovitis) both at base line and at follow up. MSUS is highly sensitive for early detection of joint involvement in JIA when compared to physical examination. Significant decrease in the mean cartilage thickness of the patients measured at follow up as compared to measures at base line.ConclusionMSUS is highly sensitive for early detection of joint involvement in JIA when compared to physical examination
Objective: The aim of this study was to assess the predictive value of endometrial thickness, morphology and vasculature using two-dimensional (2D) Doppler ultrasound on the IVF/ICSI cycle outcome. Subjects and methods: Endometrial thickness, morphology and subendometrial blood flow were assessed using transvaginal ultrasound on the day of hCG in 100 patients undergoing IVF/ICSI treatment in the period between June 2013 and January 2015. Statistical analysis was done. Results: There was no difference in the demographic features or details of ovarian stimulation between pregnant and non-pregnant women. Overall, 40 patients conceived; 23 (57.5%) of them had blood flow in zone III and 15 (37.5%) in zone II. All patients achieved pregnancy had endometrial thickness >8 mm. Using the ROC curve, the cutoff endometrial thickness for non-achieving pregnancy was 7 mm with a sensitivity and specificity of 100%. There was no significant difference in Doppler indices between pregnant and non-pregnant women. Conclusion: When the endometrial thickness is <8 mm, and if there are non-triple endometrial line and non-favorable blood flow zone on day of hCG in IVF/ICSI cycles, pregnancy is unlikely and embryo transfer should be canceled with freezing of all embryos for future transfer to increase the success rate.
Objective: To evaluate the role of color Doppler sonography in comparison with CXR and CT imaging in diagnosis of pneumonia in adults. Patients and methods: Thirty-one patients with clinical suspicion of pneumonia were assessed by chest radiography, CT and sonography. Quantitative and qualitative sonographic examination of lesions was performed using color Doppler imaging. The correlation between color Doppler and CT findings was determined. Results: Lung ultrasound showed high sensitivity (100%), specificity (93.8%) and diagnostic accuracy 96.8% in diagnosis of pneumonia. It detected air bronchogram in all cases, simple effusion in 18 cases and effusion with internal echoes in 8 cases. It was almost agreement with CT findings (K = 0.93). The sensitivity of chest X-ray was low (60%). It was moderate agreement with CT findings (K = 0.608). A significant changes were seen in flow pattern in comparison with severity of necrosis by CT (P value = 0.038). Majority of our cases reflected pulmonary arterial flow pattern that was found in 21 cases. Conclusion: Lung ultrasound with color Doppler imaging is highly accurate and valid alternatively in diagnosis of pneumonia. By qualitative and quantitative impedance measurement, pulmonary and bronchial arteries can be differentiated. The flow pattern of pulmonary arteries was an indicative of good outcome.
Background: The accurate determination of resectability in patients with pancreatic cancer is a main goal of preoperative imaging after diagnosis. With advances in surgical techniques, the definition of resectability is in evolution, and it is crucial for radiologists to have an understanding of findings that are relevant to the determination of resectability. The parallel advancements in imaging technology are aiming to improve the ability of imaging modalities to predict resectability. Fifty patients with pancreatic ductal adenocarcinoma (PDAC) were analyzed for capability of apparent diffusion coefficient (ADC) values to predict possible tumor resectability. The patients were classified into resectable and unresectable groups based on magnetic resonance (MR) imaging criteria. Logistic regression analysis was used. Receiver operator characteristic (ROC) curve was reconstructed. Results: Out of different prognostic variables, tumor size was the only significant predictor of tumor resectability. ROC curve analysis showed that ADC value is not a discriminator of tumor resectability (area under the curve (AUC) = 0.5, P value = 0.452). Conclusions: In patients with pancreatic adenocarcinoma, ADC values might be unreliable for prediction of tumor resectability in clinical practice. Low ADC value in such tumors is more attributed to fibrotic nature rather than grade of the tumor.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.