Objective: Evaluate the changes in the mandibular condyle volume and shape in growing Class II malocclusion patients, following the use of fixed functional Class II appliances (Forsus and Advacsync II). CBCT images were used to help understand which appliance might cause more changes. Methods: Twenty growing adolescent patients were randomly allocated to Two groups (Forsus and Advancesync II). A total of fourty CBCT images were taken pre- and posttreatment. The pre- and posttreatment CBCT images were segmented using a newly developed and validated semiautomatic condylar segmentation technique. and the quantitative assessment of the mean distance differences of the condyle surfaces was de using Iterative Closest Point technique. Results: A statistically significant increase in condylar volume was observed in both groups (Forsus and Advancesync II) and no significant differences in the magnitude of condylar volumes between both groups were found. There were no statistically significant changes in the mean distance differences of the condyles shape in both groups.Both groups (Forsus and Advancesync II) expressed different patterns of shape changes with no clear pattern associated with the treatment groups.
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