Background: Multimedia systems are of considerable benefit to the current age of information technology, being beneficial for teaching purposes. Valid and reliable tools are required to assess the effectiveness of such systems. The current study aimed to evaluate psychometric properties of the Persian version of a widely held multimedia usability measurement questionnaire. Methods and findings: The study followed a descriptive-analytical design, in which American Association of Orthopedic Surgeons (AAOS) methodology was firstly consulted to translate the original version into Persian. Content and Face Validity assessments were carried out through Lawshe's method. Construct validity was evaluated applying Exploratory and Confirmatory Factorial Analyses (EFA & CFA). Reliability was evaluated via Test-Retest methodology. A number of 357 medical university students and 10 survey instrument normalization experts were randomly invited for participation. In measuring stability Pearson coefficient was calculated for all sub-scales as (Attractiveness: 0.
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