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Ibibio is a Nigerian tone language, spoken in the south-east coastal region of Nigeria. Like most African languages, it is resource-limited. This presents a major challenge to conventional approaches to speech synthesis, which typically require the training of numerous predictive models of linguistic features such as the phoneme sequence (i.e., a pronunciation dictionary plus a letterto-sound model) and prosodic structure (e.g., a phrase break predictor). This training is invariably supervised, requiring a corpus of training data labelled with the linguistic feature to be predicted. In this paper, we investigate what can be achieved in the absence of many of these expensive resources, and also with a limited amount of speech recordings. We employ a statistical parametric method, because this has been found to offer good performance even on small corpora, and because it is able to directly learn the relationship between acoustics and whatever linguistic features are available, potentially We present an evaluation that compares systems that have access to varying degrees of linguistic structure. The simplest system only uses phonetic context (quinphones), and this is compared to systems with access to a richer set of context features, with or without tone marking. It is found that the use of tone marking contributes significantly to the quality of synthetic speech.Future work should therefore address the problem of tone assignment using a dictionary and the building of a prediction module for out-of-vocabulary words.

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Drug component interactions are most likely to trigger unexpected pharmacological effects with unknown causal mechanisms, hence, demanding the discovery of patterns to establish suitable and effective regimens. This paper proposes a novel framework that embeds machine learning (ML) and multidimensional scaling (MDS) techniques, for efficient prediction of patient response to antiretroviral therapy (ART). To achieve this, experiment databases were created from two independent sources: a publicly available HIV domain datasets of patients with failed treatment – hosted by the Stanford University, hereinafter referred to as the Stanford HIV database, and locally sourced datasets gathered from 13 prominent healthcare facilities treating HIV patients in Akwa Ibom State of Nigeria, hereinafter referred to as the Akwa-Ibom HIV database: with 5,780 and 3,168 individual treatment change episodes (TCEs) of HIV treatment indicators (baseline CD4 count (BCD4), followup CD4 count (FCD4), baseline viral load (BRNA), followup viral load (FRNA), and drug type combination (DType)), observed from 1,521 and 1,301 unique patient records, respectively. A hybridised (two-stage) classification system consuming the Interval Type-2 Fuzzy Logic (IT2FL) and Deep Neural Network (DNN) was employed to model and optimise patients’ response to ART with appreciable error pruning achieved through MDS. Visualisation of the experiment databases showed remarkable immunological changes in the Akwa-Ibom HIV database, as the FCD4 of TCEs clustered far above the BCD4, compared to the Stanford HIV database, where over 40% of FCD4 clustered below the BCD4. Similar changes were noticed for the RNA, as more FRNA copies clustered below the BRNA for the Akwa-Ibom datasets, compared to the Stamford datasets. DNN classification results for both databases showed best performance metrics for the Levenberg-Marquardt algorithm when compared with the resilient backpropagation algorithm, with improved drug pattern predictions for experiment with MDS. This paper is most likely to evolve an avenue that triggers interesting combination(s) for optimum patient response, while ensuring minimal side effects, as further findings revealed the superiority of the proposed approach over existing approaches.

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Outage probability is a key performance measure for real time traffic in wireless networks and is often considered as more critical than drop call probability. In this paper, we study the outage probability in a wireless mobile environment, where the interferers are distributed on the ground. Taking into consideration the background noise and the cell radius, we formulate an outage probability model coupled with observed data from Airtel Nigeria formally Zain Communications Limited, a Telecommunication company operating in Nigeria and simulate the system's performance using the Java programming language. We also present a geographical information system (GIS) solution showing the distribution of signal outages at various base stations in Akwa Ibom State (East region) of Nigeria for observed and simulated data. A performance evaluation of these data reveals that our model could greatly improve the system's performance. The results obtained allow us to study the stability of the network and evaluate the network in a more efficient and accurate manner.