This review, which is based on evaluation of information published in the last decade related to the health effects of aluminum compounds in mammals, directs attention to the well-documented effects of A1(III) compounds on phosphate metabolism. It is suggested that the toxic effects currently associated with A1(III) compounds are dependent upon the nature of A1(III) complexes formed from electron donating groups, rather than restricted to the presence of the high charge density matrix of A1(III) itself.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.