ΔAbs, the difference between the two absorbances; ACE, angiotensin converting enzyme; B 2 : bradykinin B 2 receptor; (a number [95.0%CI number, number]): effect size, 95.0% confidence interval, width lower bound, upper bound]); CCA, common carotid arteries; DTNB, 5,5'-dithio-bis-(2-nitrobenzoic acid); GMP, Good Manufacturing Practices; IC 50, the concentration of an inhibitor that inhibits the enzyme activity by 50% relative to control activity; K i , the dissociation equilibrium constant of an enzyme-inhibitor complex; K m , Michaelis constant (the concentration of the substrate at which the enzyme is at half maximal velocity); LAD, left anterior descending coronary artery; MCA, middle cerebral artery; eNOS, endothelial nitric oxide synthase; RRR, Relative Risk Reduction; tMCAO, transient middle cerebral artery occlusion; ST-115, [(S)-2-mercapto-4-methylpentanoyl]-4(S)-fluoro-Pro-Pro-3(R)-beta-Pro; tPA, tissue plasminogen activator; TTC, triphenyltetrazolium chloride.
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