With advances in deep learning and natural language processing (NLP), the analysis of medical texts is becoming increasingly important. Nonetheless, despite the importance of processing medical texts, no research on Korean medical-specific language models has been conducted. The Korean medical text is highly difficult to analyze because of the agglutinative characteristics of the language, as well as the complex terminologies in the medical domain. To solve this problem, we collected a Korean medical corpus and used it to train the language models. In this paper, we present a Korean medical language model based on deep learning NLP. The model was trained using the pre-training framework of BERT for the medical context based on a state-of-the-art Korean language model. The pre-trained model showed increased accuracies of 0.147 and 0.148 for the masked language model with next sentence prediction. In the intrinsic evaluation, the next sentence prediction accuracy improved by 0.258, which is a remarkable enhancement. In addition, the extrinsic evaluation of Korean medical semantic textual similarity data showed a 0.046 increase in the Pearson correlation, and the evaluation for the Korean medical named entity recognition showed a 0.053 increase in the F1-score.

Background The fact that medical terms require special expertise and are becoming increasingly complex makes it difficult to employ natural language processing techniques in medical informatics. Several human-validated reference standards for medical terms have been developed to evaluate word embedding models using the semantic similarity and relatedness of medical word pairs. However, there are very few reference standards in non-English languages. In addition, because the existing reference standards were developed a long time ago, there is a need to develop an updated standard to represent recent findings in medical sciences. Objective We propose a new Korean word pair reference set to verify embedding models. Methods From January 2010 to December 2020, 518 medical textbooks, 72,844 health information news, and 15,698 medical research articles were collected, and the top 10,000 medical terms were selected to develop medical word pairs. Attending physicians (n=16) participated in the verification of the developed set with 607 word pairs. Results The proportion of word pairs answered by all participants was 90.8% (551/607) for the similarity task and 86.5% (525/605) for the relatedness task. The similarity and relatedness of the word pair showed a high correlation (ρ=0.70, P<.001). The intraclass correlation coefficients to assess the interrater agreements of the word pair sets were 0.47 on the similarity task and 0.53 on the relatedness task. The final reference standard was 604 word pairs for the similarity task and 599 word pairs for relatedness, excluding word pairs with answers corresponding to outliers and word pairs that were answered by less than 50% of all the respondents. When FastText models were applied to the final reference standard word pair sets, the embedding models learning medical documents had a higher correlation between the calculated cosine similarity scores compared to human-judged similarity and relatedness scores (namu, ρ=0.12 vs with medical text for the similarity task, ρ=0.47; namu, ρ=0.02 vs with medical text for the relatedness task, ρ=0.30). Conclusions Korean medical word pair reference standard sets for semantic similarity and relatedness were developed based on medical documents from the past 10 years. It is expected that our word pair reference sets will be actively utilized in the development of medical and multilingual natural language processing technology in the future.

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BACKGROUND With advances in deep learning and natural language processing, analyzing medical texts is becoming increasingly important. Nonetheless, a study on medical-specific language models has not yet been conducted given the importance of medical texts. OBJECTIVE Korean medical text is highly difficult to analyze because of the agglutinative characteristics of the language as well as the complex terminologies in the medical domain. To solve this problem, we collected a Korean medical corpus and used it to train language models. METHODS In this paper, we present a Korean medical language model based on deep learning natural language processing. The proposed model was trained using the pre-training framework of BERT for the medical context based on a state-of-the-art Korean language model. RESULTS After pre-training, the proposed method showed increased accuracies of 0.147 and 0.148 for the masked language model with next sentence prediction. In the intrinsic evaluation, the next sentence prediction accuracy improved by 0.258, which is a remarkable enhancement. In addition, the extrinsic evaluation of Korean medical semantic textual similarity data showed a 0.046 increase in the Pearson correlation. CONCLUSIONS The results demonstrated the superiority of the proposed model for Korean medical natural language processing. We expect that our proposed model can be extended for application to various languages and domains.

BACKGROUND The fact that medical terms require special expertise and are becoming increasingly complex makes it difficult to employ natural language processing techniques in medical informatics. Several human-validated reference standards for medical terms have been developed to evaluate word embedding models using the semantic similarity and relatedness of medical word pairs. However, there are very few reference standards in non-English languages. In addition, because the existing reference standards were developed a long time ago, there is a need to develop an updated standard to represent recent findings in medical sciences. OBJECTIVE We propose a new Korean word pair reference set to verify embedding models. METHODS From January 2010 to December 2020, 518 medical textbooks, 72,844 health information news, and 15,698 medical research articles were collected, and the top 10,000 medical terms were selected to develop medical word pairs. Sixteen attending physicians participated in the verification of the developed set with 607 word pairs. RESULTS The proportion of word pairs answered by all participants was 90.8% (551/607) for the similarity task and 86.5% (525/605) for the relatedness task. The similarity and relatedness of the word pair showed a high correlation (ρ=0.70, P<.001). The intraclass correlation coefficients to assess the inter-rater agreements of the word pair sets were 0.47 on the similarity task and 0.53 on the relatedness task. The final reference standard was 604 word pairs for the similarity task and 599 word pairs for relatedness, excluding word pairs with answers corresponding to outliers and word pairs that were answered by less than 50% of all the respondents. When FastText models were applied to the final reference standard word pair sets, the embedding models learning medical documents had a higher correlation between the calculated cosine similarity scores compared to human-judged similarity and relatedness scores (ρ=0.12, namu vs. ρ=0.47, with medical text for the similarity task and ρ=0.02, with namu vs. ρ=0.30, with medical text for the relatedness task). CONCLUSIONS Korean medical word pair reference standard sets for semantic similarity and relatedness were developed based on medical documents from the past 10 years. It is expected that our word pair reference sets will be actively utilized in the development of medical and multilingual natural language processing technology in the future.