Malakoplakia is a granulomatous disease associated with an infectious etiology, usually involving the urinary tract. It reveals itself as a recurrent urinary tract infection (r-UTI), and in some cases, it is associated with impairment of renal function. Immunosuppression is one of its main associated factors, and it has been increasingly described in patients with solid organ transplantation (SOT), mainly kidney transplantation. Macroscopically, it can form masses and sometimes it may be confused with neoplasia, which is why histological findings are fundamental for the diagnosis. Here, we present a case of bladder malakoplakia, manifested by r-UTI from Escherichia coli in a patient with renal transplantation, refractory to long-term antibiotic treatment and reduction in immunosuppression, which resolved after surgical management. We also summarize the clinical characteristics of malakoplakia and compare them with previous reports in the literature on SOT.
Acute myocardial infarction without obstructive atheroesclerotic coronary diseaseMyocardial infarction with non-obstructive coronary arteries is a new definition and clinical manifestation that includes multiple cardiac conditions. The importance in its recognition and search of the etiology lies in the long-term prognosis given the higher incidence of major
La enfermedad renal crónica es una condición con alta morbilidad, mortalidad y costos elevados para los sistemas de salud que afecta todos los grupos de población con impacto significativo en su calidad de vida. Su clasificación ha sido modificada con el tiempo y aún no existe un consenso universal para diferenciar un cambio fisiológico del aclaramiento renal versus patológico. A continuación, se expone la importancia de replantear la definición y clasificación en la población general de acuerdo a la edad, incluyendo a niños y adultos.
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