No abstract

Empirical dose reductions of VTE prophylaxis are infrequently used in underweight, critically ill patients. Further studies need to be conducted that assess the safety and efficacy of reduced-dose VTE prophylactic regimens in this population to determine if acceptable efficacy can be achieved, with lower risks of bleeding.

Our results suggest that a simple automated alert could identify more than 40% of critically ill patients prescribed inappropriate antibiotic therapy for healthcare-associated infections. These data suggest that an opportunity exists to employ hospital informatics systems to improve the prescription of antibiotic therapy in ICU patients with suspected healthcare-associated infections.

No abstract

Current practice does not reflect dose reductions for neurologically injured, underweight patients. Caution should be considered when using increased doses of UFH in neurologically injured patients that are underweight and/or may be exposed to >150 units/kg/day of UFH. Continued assessment of VTE prophylaxis is needed to confirm these findings.