PURPOSE
We conducted a population-based pediatric study to determine the incidence of symptomatic kidney stones over a 25-year period and to identify factors related to variation in stone incidence during this time period.
MATERIALS AND METHODS
The Rochester Epidemiology Project was used to identify all children (ages <18 years) diagnosed with kidney stones in Olmsted County, Minnesota from 1984–2008. Medical records were reviewed to validate first time symptomatic stone-formers with identification of age-appropriate symptoms plus stone confirmation by imaging or passage. The incidence of symptomatic stones by age, gender, and time period was compared. Clinical characteristics of incident stone-formers were described.
RESULTS
There were 207 children who received a diagnostic code for kidney stones, 84 (41%) of whom were validated as incident stone-formers. The incidence rate increased 4% per calendar year (p=0.01) throughout the 25-year period. This was due to a 6% per year rise of incidence in children aged 12–17 years (p=0.02 for age x calendar year interaction) with an increase from 13 per 100,000 person-years in 1984–1990 to 36 per 100,000 person-years in 2003–2008. Computed tomography (CT) identified the stone in 6% (1/18) of adolescent stone-formers from 1984–1996 versus 76% (34/45) from 1997–2008. The incidence of spontaneous stone passage in adolescents did not increase significantly between these two time periods (16 versus 18 per 100,000 person-years, p=0.30)
CONCLUSIONS
The incidence of kidney stones increased dramatically among adolescents in the general population over a 25-year period. The exact cause of this finding remains to be determined.
Compared to the literature we found a notably lower success rate for robot-assisted laparoscopic extravesical ureteral reimplantation in the hands of 5 fellowship trained, robotically experienced pediatric urologists. More than 10% of patients required at least 1 reoperation for persistent vesicoureteral reflux or a surgical complication. Our experience suggests a higher complication rate and a lower success rate for robot-assisted laparoscopic ureteral reimplantation compared to the gold standard of open reimplantation.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.