I n d e x e d i n P u b M e d , W e b o f S c i e n c e a n d S c o p u s Yasemin Yuyucu Karabulut, et al.; The role of COL6A1 and PD-1 expressions in renal cell carcinoma.
Background: Kidney transplant is a fair option for treatment of a chronic renal failure. Although the outcome and results of kidney transplant are good, it may be associated with some complications. One of the important complications is urinary infection. Objectives: The aim of this study was to investigate the role of early removal of the catheter in renal transplant patients on the reduction of urinary tract infections. Patients and Methods:This study was conducted as a clinical trial. Around 88 transplanted patients were enrolled and randomly divided into two groups. In the first group, the patients were taken 3 days after the transplant, and in the second group, patients were removed 7 days after the Foley catcher transplant. Urine culture was performed on two occasions. Then, the patients' data were analyzed using SPSS version 20. Results: After examination of urine and analyzing the results with t test, it showed that infection of urine in the time of removal of urethral catheter was lower than 7 days after removing urethral catheter (P < 0.05). In patients in whom catheter of urethral had been removed 3 days after the operation, approximately urinary tract infection (UTI) was 50% less than those in whom urethral catheter was removed 7 days after the operation. Conclusions: Early removal of catheter has fundamental effects on UTI after kidney transplant and it seems that early removal of urethral catheter may be safe and reasonable in renal transplant of the recipient patient.
Background: After kidney transplantation, many risk factors can lead to graft rejection and force the patient to return to dialysis treatment. Objectives: This study aims to identify risk indicators of renal graft failure, such as serum creatinine, on long-term graft survival, using a novel statistical technique. Methods: In this historical cohort study, 129 patients who underwent kidney transplants were assessed and followed up from September 2003 to December 2014 in Urmia, Iran. The main outcome of the study was assessing the survival rate of kidney transplant in these subjects. In addition, the serum creatinine levels were measured repeatedly for one year after the operation, as the most important risk indicator of graft failure. In addition, the effect of other indicators on graft survival were assessed using a joint modeling of longitudinal and survival technique, using the R software, version 3.0.2. Results: One-, three-, five-, and ten-year graft survival was 93.8%, 86.8%, 76.6%, and 37.4%, respectively. The results of the joint model showed that risk indicators, such as serum creatinine level (P < 0.0001, HR = 1.82), patient's age (P = 0.006, HR = 1.03), and antithymocytes globulin (P = 0.019, HR = 2.57) had a significant relationship to graft survival. Conclusions: In general, our study showed that short-term graft failure in Iran is almost equal to the reported rates in some developed countries, but its long-term failure is rather high compared to these same countries. In this context, monitoring the postoperative risk indicators of graft rejection, such as the serum creatinine level, plays an important role in increasing the survival rate of kidney transplantation. The present model can be used to design similarly structured datasets.
BackgroundFor rapid control of bleeding as a potential surgical complication, various techniques and equipment have been developed that can be referred to as local hemostatic agents. Research shows that the Surgicel, as one of such agents, has a significant effect on reducing bleeding in most surgeries, however, in our experimental observations on patients undergoing open prostatectomy, not only no significant reduction was seen in the amount of bleeding, but also in some cases, the Surgicel led to infection. Therefore, in this study, the effect of the Surgicel on infection and bleeding in open prostatectomy was investigated.MethosThirty patients undergoing open prostatectomy were randomly divided into two groups. To control bleeding after suturing the bladder neck, the Surgicel was installed in the first group, while it was not installed in the second group. Hemoglobin, hematocrit, PT, PTT, INR, bleeding rate, and postoperative complications were evaluated in all patients.ResultsIn the studied groups, hemoglobin level and hematocrit percentage before surgery and on the first and second days after surgery along with coagulation status were compared in terms of PT, PTT, and INR. There were no significant differences between the studied variables and baseline variables.ConclusionThe present study revealed that the Surgicel in open prostatectomy cannot be effective in controlling bleeding and can lead to infection.
Introduction: Prophylactic antibiotics are used before or at the beginning of diagnostic or therapeutic intervention to reduce post-intervention infections. Objectives: The aim of this study was to compare the administration of prophylactic antibiotics in urological procedures of Imam Reza hospital in Tabriz with the standard protocol. Patients and Methods: This cross-sectional study was performed on common urological cases including 400 patients who undergo open or endoscopic surgery who received antibiotic prophylaxis before surgery to prevent urinary tract infections. Results: The mean age of the patients was 49.59 ± 17.60 years; 51.5% of the patients were female. The most common cystoscopy procedure was performed with a frequency of 27.25% and the most common antibiotic used was cefazolin with a frequency of 34.25%. It was observed that there was a discrepancy between the type of antibiotic in 4.4% and a discrepancy between the dose of antibiotics used and the standard guideline in 5.5%. The mean duration of drug administration in the studied patients was 3.28±1.59 days with a mean of three days. Regarding duration of antibiotic use, in 26% of cases was contrary to the standard guideline. Additionally, in 11.25% of cases, the continuation of prophylactic antibiotics in the studied patients was contrary to the standard guideline. Conclusion: In the present study, the time of administration of prophylactic antibiotics before urological surgeries was the most consistent with the standard guideline. In addition, most cases of discrepancy between dose and type of antibiotic were related to stent replacement and cystoscopy.
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