Atrial septal pacing resulted in a marked improvement in AF burden and symptoms. Activation of specific prevention pacing algorithms provided more continuous atrial pacing but had limited and heterogeneous effects on AF burden.
Phototherapy with narrowband ultraviolet B (NBUVB) therapy is the gold standard treatment for the treatment of vitiligo currently. The long duration of treatment is one of the major limiting factors of the therapy. Platelet Rich Plasma (PRP) is one of the promising new treatments in the arena of dermatology and has been previously tried by some authors with varying amounts of success in the treatment of vitiligo. In this study we have attempted to analyse whether the addition of PRP therapy to NBUVB therapy in the treatment of vitiligo provides any advantage in terms of the repigmentation speed. We concluded at the end of the study that addition of PRP to NBUVB therapy does not provide any advantage for faster outcomes of treatment.
Context:Trichostasis spinulosa (TS) is a common but underdiagnosed follicular disorder involving retention of successive telogen hair in the hair follicle. Laser hair removal is a newer treatment modality for TS with promising results.Aims:This study aims to evaluate the efficacy of 800 nm diode laser to treat TS in Asian patients.Subjects and Methods:We treated 50 Indian subjects (Fitzpatrick skin phototype IV–V) with untreated trichostasis spinulosa on the nose with 800 nm diode laser at fluence ranging from 22 to 30 J/cm2 and pulse width of 30 ms. The patients were given two sittings at 8 week intervals. The evaluation was done by blinded assessment of photographs by independent dermatologists.Results:Totally 45 (90%) patients had complete clearance of the lesions at the end of treatment. Five (10%) subjects needed one-third sitting for complete clearance. 45 patients had complete resolution and no recurrence even at 2 years follow-up visit. 5 patients had partial recurrence after 8–9 months and needed an extra laser session.Conclusions:Laser hair reduction in patients with TS targets and removes the hair follicles which are responsible for the plugged appearance. Due to permanent ablation of the hair bulb and bulge, the recurrence which is often seen with other modalities of treatment for TS is not observed here.
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