Schistosomiasis is a parasitic infection that is induced by different species of Schistosoma. The infection can manifest with a variety of different pathologies depending on the involved system and causative species. Schistosoma-induced appendicitis is rare in developed countries. We discuss a case of a middle-aged female who was diagnosed with acute appendicitis and underwent appendectomy. Upon histopathological examination of the resected appendix, Schistosoma infestation was identified as the underlying cause.
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