Introduction and objective:Focal cryotherapy emerged as an efficient option to treat favorable and localized prostate cancer (PCa). The purpose of this video is to describe the procedure step by step.Materials and methods:We present the case of a 68 year-old man with localized PCa in the anterior aspect of the prostate.Results:The procedure is performed under general anesthesia, with the patient in lithotomy position. Briefly, the equipment utilized includes the cryotherapy console coupled with an ultrasound system, argon and helium gas bottles, cryoprobes, temperature probes and an urethral warming catheter. The procedure starts with a real-time trans-rectal prostate ultrasound, which is used to outline the prostate, the urethra and the rectal wall. The cryoprobes are pretested and placed in to the prostate through the perineum, following a grid template, along with the temperature sensors under ultrasound guidance. A cystoscopy confirms the right positioning of the needles and the urethral warming catheter is installed. Thereafter, the freeze sequence with argon gas is started, achieving extremely low temperatures (-40°C) to induce tumor cell lysis. Sequentially, the thawing cycle is performed using helium gas. This process is repeated one time. Results among several series showed a biochemical disease-free survival between 71-93% at 9-70 month- follow-up, incontinence rates between 0-3.6% and erectile dysfunction between 0-42% (1–5).Conclusions:Focal cryotherapy is a feasible procedure to treat anterior PCa that may offer minimal morbidity, allowing good cancer control and better functional outcomes when compared to whole-gland treatment.
The present study aims to compare cavitation models in predicting the flow in small-sized cavitating venturis. Three cavitation models, namely Schnerr and Sauer model, Zwart et al. Model and Singhal et al. Model have been compared under the mixture approach. Furthermore, the performance of this device has been assessed using the concept of exergy by quantifying the exergy losses accuring in its different parts. It is found that all models are capable of reproducing the physics of cavitation phenomena within the cavitating venturi. However, the Schnerr and Sauer model return higher values than the others model. It is also observed that most of the exergy losses occur in the converging and diverging parts of the venturi due to higher pressure and velocity gradients in these regions.
The objective of the present study is to carry out a numerical study of the flow around a NACA0021 modified wing by the incorporation of sinusoidal tubercles on its leading edge at a Reynolds number equal to 225,000. The SST k-ω turbulence model is used as closure to the incompressible governing equations. Runs have been performed for several attack angles. Results show that for lower angles of attack, tubercles reduce the drag coefficient with a slight increase in lift.
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