This document addresses the selection of antifungal agents, preparation of antifungal stock solutions and dilutions for testing implementation and interpretation of test procedures, and quality control requirements for susceptibility testing of filamentous fungi (moulds) that cause invasive and cutaneous fungal infections. A standard for global application developed through the Clinical and Laboratory Standards Institute consensus process.
Aim: To study correlation between clinical features and histopathological exam of ocular surface squamous neoplasia. Materials and Methods: This is a Prospective interventional study conducted at the department of Oculoplasty of Sarojini Devi eye hospital between January 2012 to June 2013. 54 patients of freshly diagnosed OSSN were included in the study. Cases which were treated or had recurrence were excluded from the study. All the cases were examined by an experienced Ophthalmologist using Slit lamp, Snellen's chart, Gonioscope and Direct Ophthalmoscope. Informed consent was obtained from all patients. After doing routine investigations like CBP, RBS, CT, BT, HIV, HbsAG patients were posted for excision biopsy of OSSN including 4mm of surrounding normal conjunctiva under local anaesthesia. Specimen was sent for Histopathological examination for diagnosis and margin clearance. Results: Out of 54 cases 36 were males and 18 were females. 21 had dysplasia, 15 had carcinoma in situ, 18 had Squamous cell carcinoma. 33 cases had out door occupation and 21 had indoors occupation. 27 had nodular type, 15 had Leucoplakic type and 4 had diffuse type. 21 cases had corneal involvement. HPE grades 3 had mild dysplasia, 6 moderate dysplasia, 12 had severe dysplasia, 15 had carcinoma in situ, 18 had Squamous cell carcinoma. 15 cases were HIV positive and 39 cases were HIV negative.
Conclusion:Males out numbered females. Outdoor workers are more prone for OSSN. Nodular variety is commonest clinical type followed by Leucoplakic type and least common is diffuse type.
Aim: To study the efficacy of intra lesional injection of triamcinolone acetonide in treating chalazion. Materials and Method: This is a prospective interventional study conducted on 100 cases of chalazion at the department of Oculoplasty and orbital disease of Sarojini Devi eye hospital, during July 2013 to June 2015. 100 cases of chalazion who came to the out patient department of Sarojini Devi Eye Hospital were included in the study. Recurrent cases, cases of acute hordeolum internum, Lid malignancies, and children were excluded from the study. Informed consent was obtained from cases selected. They were investigated for Routine surgical profile and size of chalazion measured in millimetres by a transparent ruler. Then Injection of 0.1 ml of triamcinolone was given intra lesionally into the chalazion in minor operation theatre taking all Aseptic Precautions. Cases were followed post operatively after I st week and fourth week for reduction in size of chalazion. Result: Out of 100 cases 80 had complete resolution, 11 had reduction in size and 9 didn't respond to treatment. Conclusion: Intra lesional injection of triamcinolone is Aesthetic method of treating chalazion.
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