Triple-negative breast cancer (TNBC) is a heterogeneous disease on the pathological, molecular, and clinical levels. It represents approximately 17% of all breast cancers (BCs) and have aggressive behavior compared to other molecular subtypes. QNBC is TNBC that lacks the expression of androgen receptor (AR), Estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER-2) and accounts for 63%-87% of TNBC with more aggressive behavior than the other molecular subtypes (
Aims and objectives: Acute appendicitis is the most common surgical disease with a lifetime risk of 7-8%. Numerous studies have shown many benefits of laparoscopic appendectomy over open appendectomies, such as better visualization and identification of other abdominal pathologies that can mimic acute appendicitis. Herein, we illustrated the current incidence of non-appendicitis pathologies during laparoscopic appendectomies in our hospital. Materials and methods: A retrospective study was carried out involving patients operated for acute appendicitis laparoscopically at the Surgical Emergency Unit, Zagazig University Hospitals, Egypt, during the period from March 2017 to December 2019. The diagnosis of acute appendicitis was based on clinical examination, laboratory findings, and ultrasonography. We drew out the patients' demographic data, duration of surgery, and surgical procedure reports. Results: One hundred forty-five patients presented clinically, and confirmed by laboratory and ultrasonography with the diagnosis of acute appendicitis. Eighty-nine were males, 56 were females. The median operative time was 56.5 minutes. Eight cases (5.5%) showed a pathology other than acute appendicitis, including gynecological pathologies, Mickel's diverticulitis, inflamed sigmoid appendices epiploica, low-grade appendiceal mucinous neoplasm, and inflamed cecal diverticulum. Conclusion: Diagnosis of acute appendicitis is challenging up to date. We faced many conditions mimicking acute appendicitis during surgical intervention.
Introduction The incidence of stomal prolapse ranges from 2% to 22%. The risk factors include colostomy, the short length of the stoma, obesity, emergency surgery, and the improper (or even absence of) marking of the preoperative site for the stoma. Complicated stomal prolapse associated with severe mucosal irritation, ischemic changes, or bleeding requires surgical intervention.
Objective To describe the use of the Altemeier technique in the management of cases of complicated prolapsed stoma after failure of the local medical measures and manual reduction.
Methods Case series of three patients with past history of abdominoperineal resection of rectal cancer and permanent end colostomy presented with irreducible prolapse of the stoma. After the failure of the local measures and manual reduction, urgent surgical intervention using the modified Altemeier technique was necessary.
Results The modified Altemeier technique is simple, presents low risk of operative and postoperative complications, besides enabling an early recovery, with a lower risk of recurrence during the first 6 months after the repair.
Conclusion The modified Altemeier technique may be a valid therapeutic modality in the setting of complicated prolapsed stoma.
Background: Rectal cancer surgery had achieved remarkable evolution over the past years. Thanks to the adoption of total mesorectal excision and neoadjuvant chemoradiation, local recurrence rates dropped significantly down to 5%. Objective: This study was aimed to evaluate the functional and oncological outcome of rectal cancer management in specialized two centers. Patients and methods: This retrospective study included a total of 30 patients operated for rectal cancer, attending at Zagazig University Hospitals and Meet Ghamer Oncology Center. This study was conducted between 2017 to 2019. Results: This study included 30 cases, 16 were males and 14 were females, operative time ranged from 120-140 minutes with mean 130 minutes. Blood loss ranged between 250-600 cc. Only one case was converted to open surgery. No intraoperative complications like ureteric or bowel injuries were recorded. Postoperative complications were noted in 7 patients, of them 4 patients developed perineal wound infection and they improved with conservative management, one case developed chest infection who was improved with medical treatment, 1 patient developed stoma and sunken refashioning was successfully done, and 1 patient complained of postoperative urinary incontinence and impotence. Conclusion: It could be concluded that laparoscopic surgery improves oncologic and functional outcome better than open because of good visualization of pelvic anatomy.
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