Proliferative myositis (PM) is a rare inflammatory disease. Most commonly, the lesion occurs in the extremities. Regarding its fast growth and bizarre shape of the cellular components this entity commonly misdiagnosed and the patients undergo improper therapeutic approaches. In other words, it is often misdiagnosed as sarcoma. The diagnosis can only be made by the microscopic examination, so biopsy is mandatory. Here the authors report a patient with PM who was initially misdiagnosed as pleomorphic sarcoma of the lower extremity and explain this rare entity.Proliferative myositis should be taken into account if a fast growing, intramuscular mass occurs in the extremities.
Ewing’s sarcoma is seen mainly in patients less than 18. This aggressive tumor generally affects the axial skeleton and only rarely involves the acral regions. Ewing’s sarcoma in the foot is inordinately scarce. Clinical features are uncertain and can imitate other common diseases. This paper presents a case of 62-year-old malewith complaints of pain and swelling of the subungual area of his right great toe. The lesion was excised, and histopathological diagnosis of Ewing’s sarcoma was made. Histopathological examination, supported by immunochemical methods, remains the mainstay of diagnosis. Surgical ablation along with chemotherapy is the therapy of choice. To our knowledge, this is the first report of Ewing’s sarcoma involving the nail bed of the great toe without bone erosion. The key messages of this case report is “Subungual Ewing sarcoma is a rare case, and Ewing’s sarcoma must be kept in mind for acral lesions, especially in the adult population.”
Background: Although fine-needle aspiration biopsy (FNAB) is considered the standard for preoperative evaluation of thyroid nodules, the value of this has been questioned for different thyroid nodules size. Different pathology and radiological scoring may improve the accuracy of preoperative diagnosis of thyroid nudoles. The aim of this study was to evaluate the relation between radiology Thyrads score and Bethesda pathology score system size in two group size (≤ 10 mm and > 10 mm) of thyroid nodule in US-FNAB. Methods: There were 183 thyroid nodules between 3 mm to 35 mm who underwent US-FNAB from January 2015 to November 2016 in Shaheed Sadoughi hospital-Yazd. They were divided in to two groups (group A, 3-10 mm; group B, 11-35 mm). The patients were studied according radiology Thyrads score and Bethesda pathology score system. The relation between radiology Thyrads score and Bethesda pathology score system according groups size was analyzed by SPSS21. Results: The mean age (± standard deviation) of patients was 44.5 (± 12.8 years). Most of them were female 138 (83.6%). The frequency of final pathology diagnoses were; 35(21.2%) non diagnostic, 107 (64.8%) benign, 13 (7.9%) malignant and 10 (6.1%) suspicious. no statically significance relation between thyrads score and nodule characteristics (solid/cyst (p-value: 0.555), calcification (P value: 0.558), lymph-adenopathy (P value: 0.521), ecogenicity (P value: 0.236), margin (P value:0.149)). The spearman correlation between radiology thyroids score and Bethesda pathology score system was statistically significant. (Correlation coefficient: 0.202, P value: 0.004). Conclusions: There was a statistically significance correlation between Thyrads score and pathologic Bethesda scoring system. Decision making basis on the radiologic Thyrads score can improve the radiological diagnosis precision in nodular goiter patients.
Background: Duplex ultra-sonography is a non-invasive, non-expensive screening test for carotid disease. Intima media thickness (IMT) is appropriate for atherosclerosis process diagnosis. Leukoaraisis (LA) increase the risk of cerebrovascular accident (CVA). LA patients need preventive medication for CVA. IMT is a non-invasive diagnostic and prognostic test in LA. Objectives: The aim of this study was comparison of carotid IMT in LA patients and control group. Method: The case-control study was done on 100 LA patients and 100 controls. They were selected by simple sampling method in Shaheed Sadoughi MRI unit. Two groups member were matched by age and sex. The patient's information (age, sex, weight, height, past medical history, smoking history, ischemic heart disease (IHD), CVA and past medication) according the study checklist was collected. All statistical analysis were done by SPSS21. Results: totally 200 patients were studied, 102 in normal group and 98 in ILA group. The mean age of patients was 64.39 (± 9.12) and 47% participants were male. There were no statistical differences between hypertension and hyperlipidemia frequency in two groups (P value > 0.05). The mean of left CIMT was 0.856 (± 0.202) in normal and 0.962 (± 171) in LA groups (P value: 0.026). The mean of right CIMT was 0.853 (± 0.215) in normal and 0.973 (± 188) in LA groups (p-value: 0.024). Conclusions: LA increases the risk of CVA and dementia. The LA pathology is unknown. The epidemiological studies revealed the age, diabetes, smoking and atherosclerosis are related with LA. Our findings showed that CIMT as an atherosclerosis marker was higher in LA patients than control group.
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