The Anatolian Journal of Cardiology is an international monthly periodical on cardiology published on independent, unbiased, double-blinded and peerreview principles. The journal's publication language is English however titles of articles, abstracts and Keywords are also published in Turkish on the journal's web site.The Anatolian Journal of Cardiology aims to publish qualified and original clinical, experimental and basic research on cardiology at the international level. The journal's scope also covers editorial comments, reviews of innovations in medical education and practice, case reports, original images, scientific letters, educational articles, letters to the editor, articles on publication ethics, diagnostic puzzles, and issues in social cardiology.The target readership includes academic members, specialists, residents, and general practitioners working in the fields of adult cardiology, pediatric cardiology, cardiovascular surgery and internal medicine.
Background
:
The present study aimed to assess and compare regional strain of the right and left sides of interventricular septum in healthy subjects using velocity vector imaging analysis due to the importance of interventricular septum and limited basic information about the exact function of the interventricular septum.
Methods
The present study was conducted on 40 healthy subjects. Echocardiography was performed in the apical 4-chamber view in the left lateral decubitus position. Image analysis was done offline with velocity vector imaging; the longitudinal strain and strain rate were calculated during 3 cardiac cycles. Strain-time and strain rate-time curves in basal, middle, and apical segments of the left and right sides of interventricular septum were recorded; peak values and time to peak strain were determined.
Results
There was no significant difference between the longitudinal strain in the right and left basal (−17.7 ± 5.10% vs. −18.2 ± 5.14%,
P
= .550), middle (−17.1 ± 4.53% vs. −17.9 ± 4.29%,
P
= .197) segments, strain rate of basal (−1.1 ± 0.36 1/s vs. −1.0 ± 0.36 1/s,
P
= .350), and middle (−1.0 ± 0.30 1/s vs. −1.1 ± 0.32 1/s,
P
=0.551) segments. However, there was a significant difference between the longitudinal strain (−22.2 ± 5.55% vs. −16.6 ± 4.45%,
P
< .001) and strain rate (−1.5 ± 0.46 1/s vs. −1.1 ± 0.33 1/s,
P
< .001) of the apical segment. Time to peak strain was significantly different only in the middle segment of interventricular septum (right side: 351.0 ±11.5 ms vs.left side: 344.4 ± 13.1 ms,
P
= .004).
Conclusions
The findings of this study suggest that the right and left function of the septum was comparable in the basal and middle segments of healthy subjects; this function was significantly different in the apical segments.
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