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Our findings showed that raisin has a neuroprotective effect and improves the spatial memory in AD animal models.

Objective: Epileptogenesis after status epilepticus (SE) has a faster onset in rats treated to reduce brain levels of the anticonvulsant neurosteroid allopregnanolone with the 5α-reductase inhibitor finasteride; however, it still has to be evaluated whether treatments aimed at increasing allopregnanolone levels could result in the opposite effect of delaying epileptogenesis. This possibility could be tested using the peripherally active inhibitor of 3β-hydroxysteroid dehydrogenase/Δ 5-4 isomerase trilostane, which has been shown repeatedly to increase allopregnanolone levels in the brain.

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