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Background and Aims: Clinical characteristics and factors associated with mortality in patients admitted to the intensive care unit (ICU) in countries with low case fatality rates (CFR) are unknown. We sought to determine these in a large cohort of critically ill COVID-19 patients in Qatar and explore the early mortality predictors. Methods:We retrospectively studied the clinical characteristics and outcomes in patients admitted to the ICU at the national referral hospital for COVID-19 patients in Qatar. Logistic regression analysis was used to determine factors associated with mortality.Results: Between March 7 and July 16, 2020, a total of 1079 patients with COVID-19 were admitted to the ICU. The median (IQR) age of patients was 50 (41-59) years. Diabetes (47.3%) and hypertension (42.6%) were the most common comorbidities. In-hospital mortality was 12.6% overall and 25.9% among those requiring mechanical ventilation. Factors independently associated with mortality included older age ([OR]; 2.3 [95% CI; 1.92-2.75] for each 10-year increase in age, p < 0.001), chronic kidney disease (OR;

Cytomegalovirus (CMV) infection exists in 50-80% of the world's population in clinically undetected form due to their immunocompetent status. Here we report a case of a 42-year-old COVID-19 patient with no past medical history, who received tocilizumab, which led to a massive lower gastrointestinal bleeding not responded to medical management.

BACKGROUNDCoronavirus disease started in China as a severe pneumonia of unknown cause in late 2019 and quickly spread throughout the world with human-to-human transmission. COVID-19 was declared a pandemic in the first quarter of 2020 by the World Health Organization (WHO) 1 and has caused a significant mortality and financial resources worldwide. The pandemic is far from being over and has compromised even the most developed countries' healthcare systems. There are various risk factors for getting severe COVID-19 infection, such as patients' age and comorbidities including diabetes, cardiovascular and chronic respiratory disorders. [2][3][4] However, the role of immunosuppression therapy is still not

Critical illness-associated cerebral microbleeds and leukoencephalopathy related to COVID-19 infection are increasingly being recognized in the literature. We report seven cases of COVID-19 with microbleeds in the juxtacortical white matter and corpus callosum and one case of leukoencephalopathy.

Tension pneumomediastinum (TPM) is a rare but potentially fatal clinical entity. This leads to leakage of air into the mediastinal cavity and increased pressure on thoracic vessels, respiratory tract, and the heart. We report a series of five cases of COVID-19 complicating into acute respiratory distress syndrome and developing TPM.

This is a case of an elderly female with comorbidities and a history of cardiac transplant 13 years back, presented with diarrhea and diagnosed with COVID-19. She was hospitalized and found to have a cardiac injury and urinary tract infection, treated with antibiotics, antivirals, immunosuppressives, and required non-invasive ventilatory support.

Acute transverse myelitis is a rare disease that can behave either in a benign course where it may end up in full neurologic recovery, or permanent neurologic sequelae and death. This report describes a 52-year-old male who presented with features of acute transverse myelitis associated with COVID-19.