Aims Our aim is to describe the clinical characteristics and management of patients hospitalized with acute heart failure (HHF) and ambulatory patients with chronic heart failure (CHF) in Egypt and compare them with heart failure (HF) patients from other countries in the European Society of Cardiology-Heart Failure (ESC-HF) registry. Methods and resultsThe ESC-HF Long-term Registry is a prospective, multi-centre, observational study of patients presenting to cardiology centres in member countries of the ESC. From April 2011 to February 2014, a total of 2145 patients with HF were recruited from 20 centres all over Egypt. Of these patients, 1475 (68.8%) were hospitalized with HHF, while 670 (31.2%) had CHF. Less than one-third (32.1%) of all patients were females. HHF patients {median age of 61 years [interquartile range (IQR), 53-69]} were older than CHF patients [median age of 57 years (IQR,46-64)]; P < 0.0001. They had more diabetes mellitus (45.4% vs. 31.8%; P < 0.0001). Left ventricular ejection fraction > 45% was present in 22% of HHF vs. 25.6% of CHF (P = 0.17). Atrial fibrillation existed in about a quarter of all patients (24.5%). Ischaemic heart disease was the main cause of HF in Egyptian patients. All-cause in-hospital mortality was 5%. Egyptian patients presented at a much earlier age than in other regions in the registry. They had more diabetes mellitus. Atrial fibrillation prevalence was remarkably lower. Other co-morbidities (renal dysfunction, stroke, and peripheral arterial disease) occurred less frequently.Conclusion Patients in the Egyptian cohort exhibited distinct features from HF patients in other countries in the ESC-HF Long-term Registry.

Men and women with AHF differ significantly in baseline clinical characteristics and management but not in adverse outcomes. These findings emphasize the importance of individualized management and need for more comprehensive recruitment of women in clinical trials.

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Background: there is a strong relationship between epicardial fat thickness and severity of coronary artery disease. The impact of diabetes on severity of coronary artery disease (CAD) is well known. The possible impact of diabetes on the relationship between EFT and severity of CAD was not fully investigated. Patients and Methods: The study included 52 patients with NSTEMI (mean age: 54.3±6.7years). Patients were classified into two groups according to presence of diabetes (diabetic group (24 patients) and non-diabetic group (28 patients)). EFT was measured by transthoracic echocardiography on the right ventricle in individuals having the left lateral decubitus position GENSINI score was used to define the severity of CAD. Results: Diabetic patients had higher EFT values compared with non-diabetics (p < 0.05). EFT is independently associated with diabetes and GENSINI score in all patients (p < 0.05, for all). When patients were divided into two groups, as diabetic and non-diabetic, the association between EFT and GENSINI score was stronger in diabetic patients compared with non-diabetics (r = 0.6618; p< 0.001vs. r = 0.330; p = 0.04). Conclusion: Epicardial fat thickness is associated with GENSINI score in both diabetic and non-diabetic patients suffering from NSTEMI. Furthermore, there is a stricter relationship between EFT and GENSINI score in diabetic patients