This study aims to investigate the effect of fennel and barley seeds on 24 rats with inflicted kidneys weighing 150 ± 10g. Rats were fed on basal diet for 7 consecutive days on basal diet, then divided into 6 groups each of 4 rats. The first was negative control group fed on the basal diet, and the second was positive group injected with gentamicin (10 mg/kg body weight) twice a week for four weeks. As for the other groups, rats treated with 5%, 10%, fennel seeds (FS) and 5%, 10% barley seeds (BS). After twice a week for four weeks of the experiment, rats weight was measured, blood samples were taken for biochemical analysis. Fennel seeds (FS) 10% has best effect in lowering glucose, barley 10% improved enzyme activity Alanine transform (ALT) and fennel 5% improved high-density cholesterol (HDL-C). Barley seeds (BS) 10% has best effect on lowering triglycerides, barley 5% improved low-density lipoprotein and activity of creatinine and urea. Barley seeds (BS) 10% has best effect in lowering activity of total cholesterol and barley 5% acted better in decreasing activity of liver enzymes alkaline phosphatase and glutamic-oxaloacetic transaminase (ALP, AST). The histological investigation confirmed the fact that treatments with fennel and barley seeds mitigation the kidneys and livers diseases. Fennel and barley seeds has good effects on liver and kidney functions, glucose and lipid levels.
This work was conducted to study the effect of Jojoba oil, lavender oil and their mixture on hypercholesterolemic rats. Thirty five male albino rats, weighing (150±10g), were divided into 7 groups (5 rats each) , 25 of them fed on1.5% cholesterol+0.2% bile salts to induce hypercholesterolemia The first main group fed on basal diet as a negative control group. One of the second hypercholesterolemic main group (5 rats) fed on basal diet as apositive control group , and the other hypercholesterolemic rats fed on basal diet and treated by Jojoba oil, lavender oil (2.5% and 5%) and mixture of them 2.5% for 4 weeks. At the end of the experiment serum samples were analyzed for the following parameters: Lipid profile; total cholesterol (T.C), total bilirubin, tri-glycerides (T.G), high density lipoprotein (HDLc), low density lipoprotein (LDLc), very low density lipoprotein (VLDLc) ; urea , creatinine , uric acid ; glutamic oxaloacetic transaminase (GOT), glutamic pyruvic transaminase (GPT), alkaline phosphatase (ALP) and glucose. At the same time, the organs: Heart, kidney, liver, lungs and spleen were removed for weghting. The results indicated that treating rats with Jojoba oil, lavender oil and mixture of them decreased serum glucose, creatinine, uric acid, ALT, AST and ALP, as compared to the positive control group. It was concluded that the diet of Jojoba oil, lavender oil and mixture of them led to a significant decrease in lipid fractions ; (T.C),(T.G),(LDLc),(VLDLc) With increase of (HDL) , and these treatment are recommended to reduce the level of lipid profile for the patients with hypercholesterolemia.
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